UniProt Protein Function: | Nucleoplasmic shuttling protein. Mediates the nuclear import of EIF4E by a piggy-back mechanism. |
NCBI Summary: | The protein encoded by this gene is a nucleocytoplasmic shuttle protein for the translation initiation factor eIF4E. This shuttle protein interacts with the importin alpha-beta complex to mediate nuclear import of eIF4E. It is predominantly cytoplasmic; its own nuclear import is regulated by a nuclear localization signal and nuclear export signals. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2009] |
UniProt Code: | Q9NRA8 |
NCBI GenInfo Identifier: | 22095430 |
NCBI Gene ID: | 56478 |
NCBI Accession: | Q9NRA8.2 |
UniProt Secondary Accession: | Q9NRA8,Q8NCF2, Q9H708, B1AKL2, B1AKL3, B2RBF1, |
UniProt Related Accession: | Q9NRA8 |
Molecular Weight: | 108,329 Da |
NCBI Full Name: | Eukaryotic translation initiation factor 4E transporter |
NCBI Synonym Full Names: | eukaryotic translation initiation factor 4E nuclear import factor 1 |
NCBI Official Symbol: | EIF4ENIF1 |
NCBI Official Synonym Symbols: | 4E-T; Clast4 |
NCBI Protein Information: | eukaryotic translation initiation factor 4E transporter |
UniProt Protein Name: | Eukaryotic translation initiation factor 4E transporter |
UniProt Synonym Protein Names: | Eukaryotic translation initiation factor 4E nuclear import factor 1 |
Protein Family: | Eukaryotic translation initiation factor 4E transporter |
UniProt Gene Name: | EIF4ENIF1 |
UniProt Entry Name: | 4ET_HUMAN |