EIF4EBP2 Antibody, HRP conjugated (PACO26426)
- SKU:
- PACO26426
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Antibody type:
- Polyclonal
- Conjugation:
- HRP
Frequently bought together:
Description
抗体名: | EIF4EBP2 Antibody, HRP conjugated (PACO26426) |
抗体コード: | PACO26426 |
サイズ: | 50ug |
宿主種: | Rabbit |
申し込み: | ELISA |
推奨される希釈: | |
反応性: | Human |
免疫原: | Recombinant Human Eukaryotic translation initiation factor 4E-binding protein 2 protein (1-120AA) |
憲法: | Liquid |
ストレージバッファ: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
精製方法: | >95%, Protein G purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | HRP |
バックグラウンド: | Regulates eIF4E activity by preventing its assembly into the eIF4F complex. Mediates the regulation of protein translation by hormones, growth factors and other stimuli that signal through the MAP kinase pathway. |
シノニム: | Eukaryotic translation initiation factor 4E-binding protein 2 (4E-BP2) (eIF4E-binding protein 2), EIF4EBP2 |
UniProt Protein Function: | 4E-BP2: eukaryotic translation initiation factor 4E binding protein 2 |
UniProt Protein Details: | Protein type:Translation; Translation initiation Chromosomal Location of Human Ortholog: 10q21-q22 Cellular Component: cytoplasm Molecular Function:eukaryotic initiation factor 4E binding; protein binding; translation repressor activity Biological Process: cAMP-mediated signaling; insulin receptor signaling pathway; memory; negative regulation of translational initiation; regulation of synaptic plasticity; regulation of synaptic transmission; social behavior; TOR signaling pathway; translation |
NCBI Summary: | This gene encodes a member of the eukaryotic translation initiation factor 4E binding protein family. The gene products of this family bind eIF4E and inhibit translation initiation. However, insulin and other growth factors can release this inhibition via a phosphorylation-dependent disruption of their binding to eIF4E. Regulation of protein production through these gene products have been implicated in cell proliferation, cell differentiation and viral infection. [provided by RefSeq, Oct 2008] |
UniProt Code: | Q13542 |
NCBI GenInfo Identifier: | 34921510 |
NCBI Gene ID: | 1979 |
NCBI Accession: | Q13542.1 |
UniProt Related Accession: | Q13542 |
Molecular Weight: | 12,939 Da |
NCBI Full Name: | Eukaryotic translation initiation factor 4E-binding protein 2 |
NCBI Synonym Full Names: | eukaryotic translation initiation factor 4E binding protein 2 |
NCBI Official Symbol: | EIF4EBP2 |
NCBI Official Synonym Symbols: | 4EBP2; PHASII |
NCBI Protein Information: | eukaryotic translation initiation factor 4E-binding protein 2 |
UniProt Protein Name: | Eukaryotic translation initiation factor 4E-binding protein 2 |
UniProt Gene Name: | EIF4EBP2 |
UniProt Entry Name: | 4EBP2_HUMAN |