EHHADH Antibody (PACO06737)
- SKU:
- PACO06737
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Description
| 抗体名: | EHHADH Antibody (PACO06737) |
| 抗体コード: | PACO06737 |
| サイズ: | 50ug |
| 宿主種: | Rabbit |
| 申し込み: | ELISA, WB, IHC |
| 推奨される希釈: | ELISA:1:10000, WB:1:500-1:2000, IHC:1:100-1:300 |
| 反応性: | Human, Rat |
| 免疫原: | Synthesized peptide derived from the Internal region of human PBFE. |
| 憲法: | Liquid |
| ストレージバッファ: | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| 精製方法: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| 抗体のクローン性: | Polyclonal |
| アイソタイプ: | IgG |
| Conjugate: | Non-conjugated |
 | Western Blot analysis of Jurkat K562 NIH-3T3 cells using PBFE Polyclonal Antibody. |
 | Western Blot analysis of A549 cells using PBFE Polyclonal Antibody. |
| シノニム: | EHHADH; ECHD; Peroxisomal bifunctional enzyme; PBE; PBFE |
| UniProt Protein Function: | EHHADH: 2 isoforms of the human protein are produced by alternative splicing. |
| UniProt Protein Details: | Protein type:Amino Acid Metabolism - lysine degradation; EC 5.3.3.8; Oxidoreductase; EC 4.2.1.17; Other Amino Acids Metabolism - beta-alanine; Lipid Metabolism - fatty acid; EC 1.1.1.35; Mitochondrial; Lyase; Isomerase; Secondary Metabolites Metabolism - limonene and pinene degradation; Amino Acid Metabolism - valine, leucine and isoleucine degradation; Carbohydrate Metabolism - butanoate; Amino Acid Metabolism - tryptophan; Carbohydrate Metabolism - propanoate Chromosomal Location of Human Ortholog: 3q26.3-q28 Cellular Component: mitochondrion; peroxisome; cytosol Molecular Function:enzyme binding; dodecenoyl-CoA delta-isomerase activity; enoyl-CoA hydratase activity; coenzyme binding; 3-hydroxyacyl-CoA dehydrogenase activity; receptor binding Biological Process: fatty acid beta-oxidation; internal protein amino acid acetylation Disease: Fanconi Renotubular Syndrome 3 |
| NCBI Summary: | The protein encoded by this gene is a bifunctional enzyme and is one of the four enzymes of the peroxisomal beta-oxidation pathway. The N-terminal region of the encoded protein contains enoyl-CoA hydratase activity while the C-terminal region contains 3-hydroxyacyl-CoA dehydrogenase activity. Defects in this gene are a cause of peroxisomal disorders such as Zellweger syndrome. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2009] |
| UniProt Code: | Q08426 |
| NCBI GenInfo Identifier: | 223590229 |
| NCBI Gene ID: | 1962 |
| NCBI Accession: | Q08426.3 |
| UniProt Secondary Accession: | Q08426,Q58EZ5, A8K6Y3, B4DWG3, D3DNU0, |
| UniProt Related Accession: | Q08426 |
| Molecular Weight: | 723 |
| NCBI Full Name: | Peroxisomal bifunctional enzyme |
| NCBI Synonym Full Names: | enoyl-CoA, hydratase/3-hydroxyacyl CoA dehydrogenase |
| NCBI Official Symbol: | EHHADH |
| NCBI Official Synonym Symbols: | LBP; ECHD; LBFP; PBFE; FRTS3; L-PBE |
| NCBI Protein Information: | peroxisomal bifunctional enzyme; PBE; 3,2-trans-enoyl-CoA isomerase; peroxisomal enoyl-CoA hydratase; L-3-hydroxyacyl-CoA dehydrogenase; L-bifunctional protein, peroxisomal; enoyl-Coenzyme A, hydratase/3-hydroxyacyl Coenzyme A dehydrogenase |
| UniProt Protein Name: | Peroxisomal bifunctional enzyme |
| Protein Family: | Peroxisomal bifunctional enzyme |
| UniProt Gene Name: | EHHADH |
| UniProt Entry Name: | ECHP_HUMAN |