EHBP1 Antibody, HRP conjugated (PACO38571)
- SKU:
- PACO38571
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Antibody type:
- Polyclonal
- Conjugation:
- HRP
Frequently bought together:
Description
抗体名: | EHBP1 Antibody, HRP conjugated (PACO38571) |
抗体コード: | PACO38571 |
サイズ: | 50ug |
宿主種: | Rabbit |
申し込み: | ELISA |
推奨される希釈: | |
反応性: | Human |
免疫原: | Recombinant Human EH domain-binding protein 1 protein (1-106AA) |
憲法: | Liquid |
ストレージバッファ: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
精製方法: | >95%, Protein G purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | HRP |
バックグラウンド: | May play a role in actin reorganization. Links clathrin-mediated endocytosis to the actin cytoskeleton. |
シノニム: | EH domain-binding protein 1, EHBP1, KIAA0903 NACSIN |
UniProt Protein Function: | EHBP1: May play a role in actin reorganization. Links clathrin- mediated endocytosis to the actin cytoskeleton. Defects in EHBP1 are a cause of susceptibility to prostate cancer hereditary type 12 (HPC12). It is a condition associated with familial predisposition to cancer of the prostate. Most prostate cancers are adenocarcinomas that develop in the acini of the prostatic ducts. Other rare histopathologic types of prostate cancer that occur in approximately 5% of patients include small cell carcinoma, mucinous carcinoma, prostatic ductal carcinoma, transitional cell carcinoma, squamous cell carcinoma, basal cell carcinoma, adenoid cystic carcinoma (basaloid), signet-ring cell carcinoma and neuroendocrine carcinoma. 3 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:Vesicle Chromosomal Location of Human Ortholog: 2p15 Cellular Component: cytoplasm; plasma membrane Disease: Prostate Cancer, Hereditary, 12 |
NCBI Summary: | This gene encodes an Eps15 homology domain binding protein. The encoded protein may play a role in endocytic trafficking. A single nucleotide polymorphism in this gene is associated with an aggressive form of prostate cancer. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Feb 2010] |
UniProt Code: | Q8NDI1 |
NCBI GenInfo Identifier: | 217330570 |
NCBI Gene ID: | 23301 |
NCBI Accession: | NP_001136086.1 |
UniProt Secondary Accession: | Q8NDI1,O94977, Q53TG7, Q53TV6, Q580X2, Q6NX72, Q6PIT3 Q6QNV2, Q9NWI9, |
UniProt Related Accession: | Q8NDI1 |
Molecular Weight: | Calculated MW: 140kDaMolecular Weight: 1231 |
NCBI Full Name: | EH domain-binding protein 1 isoform 2 |
NCBI Synonym Full Names: | EH domain binding protein 1 |
NCBI Official Symbol: | EHBP1 |
NCBI Official Synonym Symbols: | HPC12; NACSIN |
NCBI Protein Information: | EH domain-binding protein 1 |
UniProt Protein Name: | EH domain-binding protein 1 |
Protein Family: | EH domain-binding protein |
UniProt Gene Name: | EHBP1 |
UniProt Entry Name: | EHBP1_HUMAN |