EFS Antibody (PACO09011)
- SKU:
- PACO09011
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Application:
- IF
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
抗体名: | EFS Antibody (PACO09011) |
抗体コード: | PACO09011 |
サイズ: | 50ul |
宿主種: | Rabbit |
申し込み: | ELISA, WB, IF |
推奨される希釈: | |
反応性: | Human, Mouse, Rat |
免疫原: | Human EFS |
憲法: | Liquid |
ストレージバッファ: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles. |
精製方法: | Antigen Affinity purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Non-conjugated |
シノニム: | embryonal Fyn-associated substrate;EFS;CAS3;CASS3;EFS1;EFS2;HEFS;SIN ; |
UniProt Protein Function: | EFS: Docking protein which plays a central coordinating role for tyrosine-kinase-based signaling related to cell adhesion. May serve as an activator of SRC and a downstream effector. Interacts with the SH3 domain of FYN and with CRK, SRC, and YES. Belongs to the CAS family. 2 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:Motility/polarity/chemotaxis; Adaptor/scaffold Chromosomal Location of Human Ortholog: 14q11.2 Cellular Component: cytoplasm Molecular Function:protein binding; protein domain specific binding |
NCBI Summary: | The longest protein isoform encoded by this gene contains an SH3 domain, which is known to be important in intracellular signal transduction. The protein encoded by a similiar gene in mice was shown to bind to SH3 domains of protein-tyrosine kinases. The function of this gene is unknown. Three alternatively spliced variants encoding different isoforms have been described for this gene. [provided by RefSeq, Mar 2013] |
UniProt Code: | O43281 |
NCBI GenInfo Identifier: | 8134421 |
NCBI Gene ID: | 10278 |
NCBI Accession: | O43281.1 |
UniProt Secondary Accession: | O43281,O43282, B2RAJ7, B4DJ56, E9PGU2, |
UniProt Related Accession: | O43281 |
Molecular Weight: | 40,957 Da |
NCBI Full Name: | Embryonal Fyn-associated substrate |
NCBI Synonym Full Names: | embryonal Fyn-associated substrate |
NCBI Official Symbol: | EFS |
NCBI Official Synonym Symbols: | SIN; CAS3; EFS1; EFS2; HEFS; CASS3 |
NCBI Protein Information: | embryonal Fyn-associated substrate |
UniProt Protein Name: | Embryonal Fyn-associated substrate |
UniProt Synonym Protein Names: | Cas scaffolding protein family member 3 |
Protein Family: | Embryonal Fyn-associated substrate |
UniProt Gene Name: | EFS |
UniProt Entry Name: | EFS_HUMAN |