EEF2 Antibody (PACO06450)
- SKU:
- PACO06450
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Application:
- IHC
- Application:
- IF
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
抗体名: | EEF2 Antibody (PACO06450) |
抗体コード: | PACO06450 |
サイズ: | 50ug |
宿主種: | Rabbit |
申し込み: | ELISA, WB, IHC, IF |
推奨される希釈: | ELISA:1:5000, WB:1:500-1:2000, IHC:1:100-1:300, IF:1:200-1:1000 |
反応性: | Human, Mouse, Rat |
免疫原: | Synthesized peptide derived from human EF-2 around the non-phosphorylation site of T56. |
憲法: | Liquid |
ストレージバッファ: | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
精製方法: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Non-conjugated |
![]() | Western Blot analysis of various cells using EF-2 Polyclonal Antibody. |
![]() | Western Blot analysis of VEC cells using EF-2 Polyclonal Antibody. |
シノニム: | EEF2; EF2; Elongation factor 2; EF-2 |
UniProt Protein Function: | EEF2: a member of the GTP-binding translation elongation factor family. An essential factor for protein synthesis. Promotes the GTP-dependent translocation of the nascent protein chain from the A-site to the P-site of the ribosome. This protein is completely inactivated by eEF2 kinase phosphorylation. eEF2 kinase is normally dependent on Ca2+ ions and calmodulin. eEF2 kinase can also be activated by PKA in response to elevated cAMP levels, which are generally increased in stress- or starvation-related conditions. A variety of treatments known to raise intracellular Ca2+ or cAMP levels have been shown to result in increased phosphorylation of eEF2, and thus to inhibit peptide-chain elongation. |
UniProt Protein Details: | Protein type:Translation elongation; Translation Chromosomal Location of Human Ortholog: 19p13.3 Cellular Component: polysome; membrane; cytoplasm; plasma membrane; cytosol; ribonucleoprotein complex; nucleus Molecular Function:GTPase activity; protein binding; GTP binding; protein kinase binding; translation elongation factor activity Biological Process: translational elongation; cellular protein metabolic process; translation; positive regulation of translation; peptidyl-diphthamide biosynthetic process from peptidyl-histidine; pathogenesis; hemopoietic progenitor cell differentiation; gene expression; post-translational protein modification Disease: Spinocerebellar Ataxia 26 |
NCBI Summary: | This gene encodes a member of the GTP-binding translation elongation factor family. This protein is an essential factor for protein synthesis. It promotes the GTP-dependent translocation of the nascent protein chain from the A-site to the P-site of the ribosome. This protein is completely inactivated by EF-2 kinase phosporylation. [provided by RefSeq, Jul 2008] |
UniProt Code: | P13639 |
NCBI GenInfo Identifier: | 119172 |
NCBI Gene ID: | 1938 |
NCBI Accession: | P13639.4 |
UniProt Secondary Accession: | P13639,Q58J86, B2RMP5, D6W618, |
UniProt Related Accession: | P13639 |
Molecular Weight: | 858 |
NCBI Full Name: | Elongation factor 2 |
NCBI Synonym Full Names: | eukaryotic translation elongation factor 2 |
NCBI Official Symbol: | EEF2 |
NCBI Official Synonym Symbols: | EF2; EF-2; EEF-2; SCA26 |
NCBI Protein Information: | elongation factor 2; polypeptidyl-tRNA translocase |
UniProt Protein Name: | Elongation factor 2 |
Protein Family: | Elongation factor |
UniProt Gene Name: | EEF2 |
UniProt Entry Name: | EF2_HUMAN |
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