EDEM2 Antibody (PACO40354)
- SKU:
- PACO40354
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
抗体名: | EDEM2 Antibody (PACO40354) |
抗体コード: | PACO40354 |
サイズ: | 50ug |
宿主種: | Rabbit |
申し込み: | ELISA, IHC |
推奨される希釈: | ELISA:1:2000-1:10000, IHC:1:20-1:200 |
反応性: | Human |
免疫原: | Recombinant Human ER degradation-enhancing alpha-mannosidase-like protein 2 protein (22-300AA) |
憲法: | Liquid |
ストレージバッファ: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
精製方法: | >95%, Protein G purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Non-conjugated |
![]() | Immunohistochemistry of paraffin-embedded human thyroid tissue using PACO40354 at dilution of 1:100. |
![]() | Immunohistochemistry of paraffin-embedded human colon tissue using PACO40354 at dilution of 1:100. |
バックグラウンド: | Initiates the endoplasmic reticulum-associated degradation (ERAD) that targets misfolded glycoproteins for degradation in an N-glycan-dependent manner. Catalyzes the first mannose trimming step, from Man9GlcNAc2 to Man8GlcNAc2. Extracts misfolded glycoproteins, but not glycoproteins undergoing productive folding, from the calnexin cycle. |
シノニム: | ER degradation-enhancing alpha-mannosidase-like protein 2, EDEM2, C20orf31 C20orf49 |
NCBI Summary: | In the endoplasmic reticulum (ER), misfolded proteins are retrotranslocated to the cytosol and degraded by the proteasome in a process known as ER-associated degradation (ERAD). EDEM2 belongs to a family of proteins involved in ERAD of glycoproteins (Mast et al., 2005 [PubMed 15537790]).[supplied by OMIM, Mar 2008] |
UniProt Code: | Q9BV94 |
NCBI GenInfo Identifier: | 33990680 |
NCBI Gene ID: | 55741 |
NCBI Accession: | BC001371.2 |
UniProt Related Accession: | Q9BV94 |
Molecular Weight: | |
NCBI Full Name: | Homo sapiens ER degradation enhancer, mannosidase alpha-like 2, mRNA |
NCBI Synonym Full Names: | ER degradation enhancing alpha-mannosidase like protein 2 |
NCBI Official Symbol: | EDEM2 |
NCBI Official Synonym Symbols: | C20orf31; C20orf49; bA4204.1 |
NCBI Protein Information: | ER degradation-enhancing alpha-mannosidase-like protein 2 |
UniProt Protein Name: | |
Protein Family: | ER degradation-enhancing alpha-mannosidase-like protein |
UniProt Gene Name: |