ECI2 Antibody (PACO55090)
- SKU:
- PACO55090
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Rat
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
抗体名: | ECI2 Antibody (PACO55090) |
抗体コード: | PACO55090 |
サイズ: | 50ug |
宿主種: | Rabbit |
申し込み: | ELISA, WB, IHC |
推奨される希釈: | ELISA:1:2000-1:10000, WB:1:500-1:5000, IHC:1:20-1:200 |
反応性: | Human, Rat, Mouse |
免疫原: | Recombinant Human Enoyl-CoA delta isomerase 2, mitochondrial protein (119-219AA) |
憲法: | Liquid |
ストレージバッファ: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
精製方法: | >95%, Protein G purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Non-conjugated |
Western Blot. Positive WB detected in: Rat heart tissue, Mouse heart tissue, Mouse liver tissue. All lanes: ECI2 antibody at 2.7µg/ml. Secondary. Goat polyclonal to rabbit IgG at 1/50000 dilution. Predicted band size: 44, 40 kDa. Observed band size: 44 kDa. | |
Immunohistochemistry of paraffin-embedded human liver tissue using PACO55090 at dilution of 1:100. |
バックグラウンド: | Able to isomerize both 3-cis and 3-trans double bonds into the 2-trans form in a range of enoyl-CoA species. Has a preference for 3-trans substrates (By similarity). |
シノニム: | Enoyl-CoA delta isomerase 2, mitochondrial (EC 5.3.3.8) (DRS-1) (Delta(3),delta(2)-enoyl-CoA isomerase) (D3,D2-enoyl-CoA isomerase) (Diazepam-binding inhibitor-related protein 1) (DBI-related protein 1) (Dodecenoyl-CoA isomerase) (Hepatocellular carcinoma-associated antigen 88) (Peroxisomal 3,2-trans-enoyl-CoA isomerase) (pECI) (Renal carcinoma antigen NY-REN-1), ECI2, DRS1 HCA88 PECI |
UniProt Protein Function: | PECI: Able to isomerize both 3-cis and 3-trans double bonds into the 2-trans form in a range of enoyl-CoA species. Has a preference for 3-trans substrates. 2 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:Isomerase; EC 5.3.3.8; Lipid Metabolism - fatty acid Chromosomal Location of Human Ortholog: 6p24.3 Cellular Component: intracellular membrane-bound organelle; membrane; mitochondrion; nucleoplasm; peroxisomal matrix Molecular Function:dodecenoyl-CoA delta-isomerase activity; receptor binding Biological Process: cellular lipid metabolic process |
NCBI Summary: | This gene encodes a member of the hydratase/isomerase superfamily. The protein encoded is a key mitochondrial enzyme involved in beta-oxidation of unsaturated fatty acids. It catalyzes the transformation of 3-cis and 3-trans-enoyl-CoA esters arising during the stepwise degradation of cis-, mono-, and polyunsaturated fatty acids to the 2-trans-enoyl-CoA intermediates. Alternatively spliced transcript variants have been described. [provided by RefSeq, Aug 2011] |
UniProt Code: | O75521 |
NCBI GenInfo Identifier: | 257051079 |
NCBI Gene ID: | 10455 |
NCBI Accession: | O75521.4 |
UniProt Secondary Accession: | O75521,Q5JYK5, Q5JYK7, Q7L124, Q8N0X0, Q9BUE9, Q9H0T9 Q9NQH1, Q9NYH7, Q9UN55, |
UniProt Related Accession: | O75521 |
Molecular Weight: | 39,609 Da |
NCBI Full Name: | Enoyl-CoA delta isomerase 2, mitochondrial |
NCBI Synonym Full Names: | enoyl-CoA delta isomerase 2 |
NCBI Official Symbol: | ECI2 |
NCBI Official Synonym Symbols: | DRS1; PECI; ACBD2; DRS-1; HCA88; dJ1013A10.3 |
NCBI Protein Information: | enoyl-CoA delta isomerase 2, mitochondrial |
UniProt Protein Name: | Enoyl-CoA delta isomerase 2, mitochondrial |
UniProt Synonym Protein Names: | DRS-1; Delta(3),delta(2)-enoyl-CoA isomerase; D3,D2-enoyl-CoA isomerase; Diazepam-binding inhibitor-related protein 1; DBI-related protein 1; Dodecenoyl-CoA isomerase; Hepatocellular carcinoma-associated antigen 88; Peroxisomal 3,2-trans-enoyl-CoA isomerase; pECI; Renal carcinoma antigen NY-REN-1 |
Protein Family: | Enoyl-CoA delta isomerase |
UniProt Gene Name: | ECI2 |
UniProt Entry Name: | ECI2_HUMAN |