DTNB Antibody (PACO16207)
- SKU:
- PACO16207
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
抗体名: | DTNB Antibody (PACO16207) |
抗体コード: | PACO16207 |
サイズ: | 50ul |
宿主種: | Rabbit |
申し込み: | ELISA, IHC |
推奨される希釈: | ELISA:1:2000-1:5000, IHC:1:50-1:200 |
反応性: | Human |
免疫原: | Fusion protein of human DTNB |
憲法: | Liquid |
ストレージバッファ: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
精製方法: | Antigen affinity purification |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Non-conjugated |
![]() | The image on the left is immunohistochemistry of paraffin-embedded Human prostate cancer tissue using PACO16207(DTNB Antibody) at dilution 1/50, on the right is treated with fusion protein. (Original magnification: x200). |
![]() | The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using PACO16207(DTNB Antibody) at dilution 1/50, on the right is treated with fusion protein. (Original magnification: x200). |
バックグラウンド: | This gene encodes dystrobrevin beta, a component of the dystrophin-associated protein complex (DPC). The DPC consists of dystrophin and several integral and peripheral membrane proteins, including dystroglycans, sarcoglycans, syntrophins and dystrobrevin α and beta. The DPC localizes to the sarcolemma and its disruption is associated with various forms of muscular dystrophy. Dystrobrevin β is thought to interact with syntrophin and the DP71 short form of dystrophin. Alternatively spliced transcript variants encoding different isoforms have been identified. |
シノニム: | dystrobrevin, beta |
UniProt Protein Function: | DTNB: dystrobrevin beta, a component of the dystrophin-associated protein complex (DPC). The DPC consists of dystrophin and several integral and peripheral membrane proteins, including dystroglycans, sarcoglycans, syntrophins and dystrobrevin alpha and beta. The DPC localizes to the sarcolemma and its disruption is associated with various forms of muscular dystrophy. Dystrobrevin beta is thought to interact with syntrophin and the DP71 short form of dystrophin. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008] |
UniProt Protein Details: | Protein type:Calcium-binding; Motility/polarity/chemotaxis Chromosomal Location of Human Ortholog: 2p24 Cellular Component: cytoplasm; synapse Molecular Function:zinc ion binding |
NCBI Summary: | This gene encodes dystrobrevin beta, a component of the dystrophin-associated protein complex (DPC). The DPC consists of dystrophin and several integral and peripheral membrane proteins, including dystroglycans, sarcoglycans, syntrophins and dystrobrevin alpha and beta. The DPC localizes to the sarcolemma and its disruption is associated with various forms of muscular dystrophy. Dystrobrevin beta is thought to interact with syntrophin and the DP71 short form of dystrophin. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008] |
UniProt Code: | O60941 |
NCBI GenInfo Identifier: | 13626370 |
NCBI Gene ID: | 1838 |
NCBI Accession: | O60941.1 |
UniProt Secondary Accession: | O60941,O43782, O60881, O75538, Q86VR4, Q96AW0, Q9UE14 Q9UE15, Q9UE16, B7Z733, F5GZG4, G5E9F6, |
UniProt Related Accession: | O60941 |
Molecular Weight: | 69,294 Da |
NCBI Full Name: | Dystrobrevin beta |
NCBI Synonym Full Names: | dystrobrevin, beta |
NCBI Official Symbol: | DTNB |
NCBI Protein Information: | dystrobrevin beta; DTN-B; beta-dystrobrevin |
UniProt Protein Name: | Dystrobrevin beta |
UniProt Synonym Protein Names: | Beta-dystrobrevin |
Protein Family: | Dystrobrevin |
UniProt Gene Name: | DTNB |
UniProt Entry Name: | DTNB_HUMAN |