DPYSL4 Antibody (PACO17725)
- SKU:
- PACO17725
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
抗体名: | DPYSL4 Antibody (PACO17725) |
抗体コード: | PACO17725 |
サイズ: | 50ul |
宿主種: | Rabbit |
申し込み: | ELISA, WB, IHC |
推奨される希釈: | ELISA:1:1000-1:5000, WB:1:500-1:1000, IHC:1:25-1:100 |
反応性: | Human, Mouse, Rat |
免疫原: | Synthetic peptide of human DPYSL4 |
憲法: | Liquid |
ストレージバッファ: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
精製方法: | Antigen affinity purification |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Non-conjugated |
The image on the left is immunohistochemistry of paraffin-embedded Human ovarian cancer tissue using PACO17725(DPYSL4 Antibody) at dilution 1/15, on the right is treated with synthetic peptide. (Original magnification: x200). | |
Gel: 8%SDS-PAGE, Lysate: 30 μg, Lane: Human fetal brain tissue, Primary antibody: PACO17725(DPYSL4 Antibody) at dilution 1/500, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 20 seconds. | |
The image on the left is immunohistochemistry of paraffin-embedded Human cervical cancer tissue using PACO17725(DPYSL4 Antibody) at dilution 1/15, on the right is treated with synthetic peptide. (Original magnification: x200). |
バックグラウンド: | Collapsin response mediator protein 3 is an enzyme that in humans is encoded by the CRMP3 gene.It is necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton.And plays a role in axon guidance, neuronal growth cone collapse and cell migration.Homotetramer, and heterotetramer with CRMP1, DPYSL2, DPYSL3 or DPYSL5. Interacts with PLEXA1. Phosphorylated upon DNA damage, probably by ATM or ATR. |
シノニム: | dihydropyrimidinase-like 4 |
UniProt Protein Function: | CRMP-3: Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. Plays a role in axon guidance, neuronal growth cone collapse and cell migration. Belongs to the DHOase family. Hydantoinase/dihydropyrimidinase subfamily. |
UniProt Protein Details: | Protein type:Unknown function Chromosomal Location of Human Ortholog: 10q26 Cellular Component: cytosol Molecular Function:filamin binding; hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds; protein binding Biological Process: metabolic process; nervous system development |
UniProt Code: | O14531 |
NCBI GenInfo Identifier: | 190194363 |
NCBI Gene ID: | 10570 |
NCBI Accession: | NP_006417.2 |
UniProt Secondary Accession: | O14531,O00240, Q5T0Q7, B2RMQ1, D3DRG5, |
UniProt Related Accession: | O14531 |
Molecular Weight: | 61,878 Da |
NCBI Full Name: | dihydropyrimidinase-related protein 4 |
NCBI Synonym Full Names: | dihydropyrimidinase like 4 |
NCBI Official Symbol: | DPYSL4 |
NCBI Official Synonym Symbols: | CRMP3; DRP-4; ULIP4 |
NCBI Protein Information: | dihydropyrimidinase-related protein 4 |
UniProt Protein Name: | Dihydropyrimidinase-related protein 4 |
UniProt Synonym Protein Names: | Collapsin response mediator protein 3; CRMP-3; UNC33-like phosphoprotein 4; ULIP-4 |
UniProt Gene Name: | DPYSL4 |
UniProt Entry Name: | DPYL4_HUMAN |