DPEP1 Antibody, Biotin conjugated (PACO63982)
- SKU:
- PACO63982
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Antibody type:
- Polyclonal
- Conjugation:
- Biotin
Frequently bought together:
Description
抗体名: | DPEP1 Antibody, Biotin conjugated (PACO63982) |
抗体コード: | PACO63982 |
サイズ: | 50ul |
宿主種: | Rabbit |
申し込み: | ELISA |
推奨される希釈: | |
反応性: | Human |
免疫原: | Recombinant Human Dipeptidase 1 protein (23-252AA) |
憲法: | Liquid |
ストレージバッファ: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
精製方法: | >95%, Antigen Affinity purified & Affinity purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Biotin |
バックグラウンド: | Hydrolyzes a wide range of dipeptides. Implicated in the renal metabolism of glutathione and its conjugates. Converts leukotriene D4 to leukotriene E4; it may play an important role in the regulation of leukotriene activity. |
シノニム: | Dipeptidase 1 (EC 3.4.13.19) (Dehydropeptidase-I) (Microsomal dipeptidase) (Renal dipeptidase) (hRDP), DPEP1, MDP RDP |
UniProt Protein Function: | DPEP1: Hydrolyzes a wide range of dipeptides. Implicated in the renal metabolism of glutathione and its conjugates. Converts leukotriene D4 to leukotriene E4; it may play an important role in the regulation of leukotriene activity. Belongs to the peptidase M19 family. |
UniProt Protein Details: | Protein type:EC 3.4.13.19; Membrane protein, GPI anchor; Protease Chromosomal Location of Human Ortholog: 16q24.3 Cellular Component: extracellular space; microvillus membrane; apical part of cell; apical plasma membrane; plasma membrane; nucleus; cell junction Molecular Function:protein binding; metalloexopeptidase activity; zinc ion binding; dipeptidyl-peptidase activity; caspase inhibitor activity Biological Process: glutathione metabolic process; xenobiotic metabolic process; arachidonic acid metabolic process; leukotriene metabolic process; negative regulation of caspase activity; homocysteine metabolic process; proteolysis; negative regulation of cell migration; antibiotic metabolic process; negative regulation of apoptosis |
NCBI Summary: | The protein encoded by this gene is a kidney membrane enzyme involved in the metabolism of glutathione and other similar proteins by dipeptide hydrolysis. The encoded protein is known to regulate leukotriene activity by catalyzing the conversion of leukotriene D4 to leukotriene E4. This protein uses zinc as a cofactor and acts as a disulfide-linked homodimer. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jan 2012] |
UniProt Code: | P16444 |
NCBI GenInfo Identifier: | 92090943 |
NCBI Gene ID: | 1800 |
NCBI Accession: | P16444.3 |
UniProt Secondary Accession: | P16444,Q96AK2, D3DX80, |
UniProt Related Accession: | P16444 |
Molecular Weight: | 411 |
NCBI Full Name: | Dipeptidase 1 |
NCBI Synonym Full Names: | dipeptidase 1 (renal) |
NCBI Official Symbol: | DPEP1 |
NCBI Official Synonym Symbols: | MDP; RDP; MBD1 |
NCBI Protein Information: | dipeptidase 1; hRDP; renal dipeptidase; dehydropeptidase-I; microsomal dipeptidase |
UniProt Protein Name: | Dipeptidase 1 |
UniProt Synonym Protein Names: | Dehydropeptidase-I; Microsomal dipeptidase; Renal dipeptidase; hRDP |
Protein Family: | Dipeptidase |
UniProt Gene Name: | DPEP1 |
UniProt Entry Name: | DPEP1_HUMAN |