DNMT3L Antibody (PACO51174)
- SKU:
- PACO51174
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Application:
- IF
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
抗体名: | DNMT3L Antibody (PACO51174) |
抗体コード: | PACO51174 |
サイズ: | 50ug |
宿主種: | Rabbit |
申し込み: | ELISA, WB, IF |
推奨される希釈: | ELISA:1:2000-1:10000, WB:1:500-1:5000, IF:1:50-1:200 |
反応性: | Human |
免疫原: | Recombinant Human DNA (cytosine-5)-methyltransferase 3-like protein (1-234AA) |
憲法: | Liquid |
ストレージバッファ: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
精製方法: | >95%, Protein G purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Non-conjugated |
![]() | Immunofluorescent analysis of Hela cells using PACO51174 at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L). |
![]() | Western Blot. Positive WB detected in: PC-3 whole cell lysate, HepG2 whole cell lysate, A549 whole cell lysate. All lanes: DNMT3L antibody at 3.4µg/ml. Secondary. Goat polyclonal to rabbit IgG at 1/50000 dilution. Predicted band size: 44 kDa. Observed band size: 44 kDa. |
バックグラウンド: | Catalytically inactive regulatory factor of DNA methyltransferases. It is essential for the function of DNMT3A and DNMT3B. Activates DNMT3A and DNMT3B by binding to their catalytic domain. Accelerates the binding of DNA and AdoMet to the methyltransferases and dissociates from the complex after DNA binding to the methyltransferases. Recognizes unmethylated histone H3 lysine 4 (H3K4) and induces de novo DNA methylation by recruitment or activation of DNMT3. |
シノニム: | DNA (cytosine-5)-methyltransferase 3-like, DNMT3L |
UniProt Code: | Q9UJW3 |
NCBI GenInfo Identifier: | 334302913 |
NCBI Gene ID: | 29947 |
NCBI Accession: | Q9UJW3.3 |
Molecular Weight: | 45kDa |
NCBI Full Name: | DNA (cytosine-5)-methyltransferase 3-like |
UniProt Protein Name: | DNA (cytosine-5)-methyltransferase 3-like |
Protein Family: | DNA (cytosine-5)-methyltransferase |
UniProt Gene Name: | DNMT3L |
UniProt Entry Name: | DNM3L_HUMAN |