DNAJB11 Antibody (PACO53578)
- SKU:
- PACO53578
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- IHC
- Application:
- IF
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
抗体名: | DNAJB11 Antibody (PACO53578) |
抗体コード: | PACO53578 |
サイズ: | 50ug |
宿主種: | Rabbit |
申し込み: | ELISA, IHC, IF |
推奨される希釈: | ELISA:1:2000-1:10000, IHC:1:20-1:200, IF:1:50-1:200 |
反応性: | Human |
免疫原: | Recombinant Human DnaJ homolog subfamily B member 11 protein (53-238AA) |
憲法: | Liquid |
ストレージバッファ: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
精製方法: | >95%, Protein G purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Non-conjugated |
Immunohistochemistry of paraffin-embedded human placenta tissue using PACO53578 at dilution of 1:100. | |
Immunofluorescent analysis of HepG2 cells using PACO53578 at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L). |
バックグラウンド: | Serves as a co-chaperone for HSPA5. Binds directly to both unfolded proteins that are substrates for ERAD and nascent unfolded peptide chains, but dissociates from the HSPA5-unfolded protein complex before folding is completed. May help recruiting HSPA5 and other chaperones to the substrate. Stimulates HSPA5 ATPase activity. |
シノニム: | DnaJ homolog subfamily B member 11 (APOBEC1-binding protein 2) (ABBP-2) (DnaJ protein homolog 9) (ER-associated DNAJ) (ER-associated Hsp40 co-chaperone) (Endoplasmic reticulum DNA J domain-containing protein 3) (ER-resident protein ERdj3) (ERdj3) (ERj3p) (HEDJ) (Human DnaJ protein 9) (hDj-9) (PWP1-interacting protein 4), DNAJB11, EDJ ERJ3 HDJ9 |
UniProt Protein Function: | DNAJB11: Serves as a co-chaperone for HSPA5. Binds directly to both unfolded proteins that are substrates for ERAD and nascent unfolded peptide chains, but dissociates from the HSPA5-unfolded protein complex before folding is completed. May help recruiting HSPA5 and other chaperones to the substrate. Stimulates HSPA5 ATPase activity. |
UniProt Protein Details: | Protein type:Secreted; Secreted, signal peptide; Endoplasmic reticulum; RNA processing; Chaperone Chromosomal Location of Human Ortholog: 3q27.3 Cellular Component: membrane; endoplasmic reticulum; endoplasmic reticulum lumen; nucleus Molecular Function:protein binding; unfolded protein binding Biological Process: unfolded protein response, activation of signaling protein activity; cellular protein metabolic process; protein folding; unfolded protein response; mRNA modification |
NCBI Summary: | This gene encodes a soluble glycoprotein of the endoplasmic reticulum (ER) lumen that functions as a co-chaperone of binding immunoglobulin protein, a 70 kilodalton heat shock protein chaperone required for the proper folding and assembly of proteins in the ER. The encoded protein contains a highly conserved J domain of about 70 amino acids with a characteristic His-Pro-Asp (HPD) motif and may regulate the activity of binding immunoglobulin protein by stimulating ATPase activity. [provided by RefSeq, Mar 2014] |
UniProt Code: | Q9UBS4 |
NCBI GenInfo Identifier: | 18203497 |
NCBI Gene ID: | 51726 |
NCBI Accession: | Q9UBS4.1 |
UniProt Secondary Accession: | Q9UBS4,Q542Y5, Q542Y9, Q6IAQ8, Q96JC6, |
UniProt Related Accession: | Q9UBS4 |
Molecular Weight: | 358 |
NCBI Full Name: | DnaJ homolog subfamily B member 11 |
NCBI Synonym Full Names: | DnaJ (Hsp40) homolog, subfamily B, member 11 |
NCBI Official Symbol: | DNAJB11 |
NCBI Official Synonym Symbols: | DJ9; EDJ; Dj-9; ERj3; ABBP2; ERdj3; ERj3p; ABBP-2; UNQ537; PRO1080 |
NCBI Protein Information: | dnaJ homolog subfamily B member 11; DnaJ protein 9; APOBEC1-binding protein 2; ER-resident protein ERdj3; PWP1-interacting protein 4; ER-associated DNAJ protein 3; ER-associated Hsp40 co-chaperone; endoplasmic reticulum DNA J domain-containing protein 3 |
UniProt Protein Name: | DnaJ homolog subfamily B member 11 |
UniProt Synonym Protein Names: | APOBEC1-binding protein 2; ABBP-2; DnaJ protein homolog 9; ER-associated DNAJ; ER-associated Hsp40 co-chaperone; Endoplasmic reticulum DNA J domain-containing protein 3; ER-resident protein ERdj3; ERdj3; ERj3p; HEDJ; Human DnaJ protein 9; hDj-9; PWP1-interacting protein 4 |
Protein Family: | DnaJ homolog subfamily |
UniProt Gene Name: | DNAJB11 |
UniProt Entry Name: | DJB11_HUMAN |