DNAJA1 Antibody, HRP conjugated (PACO45771)
- SKU:
- PACO45771
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Antibody type:
- Polyclonal
- Conjugation:
- HRP
Description
抗体名: | DNAJA1 Antibody, HRP conjugated (PACO45771) |
抗体コード: | PACO45771 |
サイズ: | 50ug |
宿主種: | Rabbit |
申し込み: | ELISA |
推奨される希釈: | |
反応性: | Human |
免疫原: | Recombinant Human DnaJ homolog subfamily A member 1 protein (8-106AA) |
憲法: | Liquid |
ストレージバッファ: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
精製方法: | >95%, Protein G purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | HRP |
バックグラウンド: | Co-chaperone for HSPA8/Hsc70. Stimulates ATP hydrolysis, but not the folding of unfolded proteins mediated by HSPA1A (in vitro). Plays a role in protein transport into mitochondria via its role as co-chaperone. Functions as co-chaperone for HSPA1B and negatively regulates the translocation of BAX from the cytosol to mitochondria in response to cellular stress, thereby protecting cells against apoptosis. Promotes apoptosis in response to cellular stress mediated by exposure to anisomycin or UV. |
シノニム: | DnaJ homolog subfamily A member 1 (DnaJ protein homolog 2) (HSDJ) (Heat shock 40 kDa protein 4) (Heat shock protein J2) (HSJ-2) (Human DnaJ protein 2) (hDj-2), DNAJA1, DNAJ2 HDJ2 HSJ2 HSPF4 |
UniProt Protein Function: | DNAJA1: Co-chaperone of Hsc70. Seems to play a role in protein import into mitochondria. |
UniProt Protein Details: | Protein type:Chaperone; Nuclear receptor co-regulator Chromosomal Location of Human Ortholog: 9p13.3 Cellular Component: membrane; mitochondrion; perinuclear region of cytoplasm; cytosol; nucleus; ubiquitin ligase complex Molecular Function:protein binding; G-protein-coupled receptor binding; low-density lipoprotein receptor binding; chaperone binding; metal ion binding; ubiquitin protein ligase binding; unfolded protein binding; Hsp70 protein binding; ATP binding Biological Process: negative regulation of JNK activity; protein folding; positive regulation of apoptosis; DNA damage response, detection of DNA damage; response to unfolded protein; regulation of protein transport; sperm motility; response to heat; androgen receptor signaling pathway; spermatogenesis; protein refolding; negative regulation of protein ubiquitination; negative regulation of apoptosis |
UniProt Code: | P31689 |
NCBI GenInfo Identifier: | 1706474 |
NCBI Gene ID: | 3301 |
NCBI Accession: | P31689.2 |
UniProt Secondary Accession: | P31689,Q5T7Q0, Q86TL9, |
UniProt Related Accession: | P31689 |
Molecular Weight: | 397 |
NCBI Full Name: | DnaJ homolog subfamily A member 1 |
NCBI Synonym Full Names: | DnaJ (Hsp40) homolog, subfamily A, member 1 |
NCBI Official Symbol: | DNAJA1 |
NCBI Official Synonym Symbols: | DJ-2; DjA1; HDJ2; HSDJ; HSJ2; HSPF4; NEDD7; hDJ-2 |
NCBI Protein Information: | dnaJ homolog subfamily A member 1; HSJ-2; human DnaJ protein 2; heat shock protein J2; dnaJ protein homolog 2; heat shock 40 kDa protein 4; heat shock protein, DNAJ-like 2; neural precursor cell expressed, developmentally down-regulated 7 |
UniProt Protein Name: | DnaJ homolog subfamily A member 1 |
UniProt Synonym Protein Names: | DnaJ protein homolog 2; HSDJ; Heat shock 40 kDa protein 4; Heat shock protein J2; HSJ-2; Human DnaJ protein 2; hDj-2 |
UniProt Gene Name: | DNAJA1 |
UniProt Entry Name: | DNJA1_HUMAN |