DLL3 Antibody (PACO41746)
- SKU:
- PACO41746
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
抗体名: | DLL3 Antibody (PACO41746) |
抗体コード: | PACO41746 |
サイズ: | 50ug |
宿主種: | Rabbit |
申し込み: | ELISA, IHC |
推奨される希釈: | ELISA:1:2000-1:10000, IHC:1:500-1:1000 |
反応性: | Human |
免疫原: | Recombinant Human Delta-like protein 3 protein (27-492AA) |
憲法: | Liquid |
ストレージバッファ: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
精製方法: | >95%, Protein G purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Non-conjugated |
![]() | IHC image of PACO41746 diluted at 1:700 and staining in paraffin-embedded human liver tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system. |
![]() | IHC image of PACO41746 diluted at 1:700 and staining in paraffin-embedded human brain tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system. |
バックグラウンド: | Inhibits primary neurogenesis. May be required to divert neurons along a specific differentiation pathway. Plays a role in the formation of somite boundaries during segmentation of the paraxial mesoderm. |
シノニム: | Delta-like protein 3 (Drosophila Delta homolog 3) (Delta3), DLL3 |
UniProt Protein Function: | DLL3: Inhibits primary neurogenesis. May be required to divert neurons along a specific differentiation pathway. Plays a role in the formation of somite boundaries during segmentation of the paraxial mesoderm. Can bind and activate Notch-1 or another Notch receptor. |
UniProt Protein Details: | Protein type:Cell development/differentiation; Membrane protein, integral Chromosomal Location of Human Ortholog: 19q13 Cellular Component: integral to membrane Molecular Function:Notch binding Biological Process: compartment specification; paraxial mesoderm development; Notch signaling pathway; somitogenesis; skeletal development; negative regulation of neurogenesis Disease: Spondylocostal Dysostosis 1, Autosomal Recessive |
NCBI Summary: | This gene encodes a member of the delta protein ligand family. This family functions as Notch ligands that are characterized by a DSL domain, EGF repeats, and a transmembrane domain. Mutations in this gene cause autosomal recessive spondylocostal dysostosis 1. Two transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jul 2008] |
UniProt Code: | Q9NYJ7 |
NCBI GenInfo Identifier: | 45243561 |
NCBI Gene ID: | 10683 |
NCBI Accession: | NP_982353.1 |
UniProt Secondary Accession: | Q9NYJ7,Q8NBS4, E9PFG2, |
UniProt Related Accession: | Q9NYJ7 |
Molecular Weight: | |
NCBI Full Name: | delta-like protein 3 isoform 2 |
NCBI Synonym Full Names: | delta-like 3 (Drosophila) |
NCBI Official Symbol: | DLL3 |
NCBI Official Synonym Symbols: | SCDO1 |
NCBI Protein Information: | delta-like protein 3; delta3; drosophila Delta homolog 3 |
UniProt Protein Name: | Delta-like protein 3 |
UniProt Synonym Protein Names: | Drosophila Delta homolog 3 |
Protein Family: | Delta-like protein |
UniProt Gene Name: | DLL3 |
UniProt Entry Name: | DLL3_HUMAN |
Antibodies |
Anti-DLL3 Antibody (CAB18108) |
Secondary Antibody |
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
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