DHX9 Antibody, HRP conjugated (PACO35211)
- SKU:
- PACO35211
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Antibody type:
- Polyclonal
- Conjugation:
- HRP
Frequently bought together:
Description
抗体名: | DHX9 Antibody, HRP conjugated (PACO35211) |
抗体コード: | PACO35211 |
サイズ: | 50ug |
宿主種: | Rabbit |
申し込み: | ELISA |
推奨される希釈: | |
反応性: | Human |
免疫原: | Recombinant Human ATP-dependent RNA helicase A protein (325-840AA) |
憲法: | Liquid |
ストレージバッファ: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
精製方法: | >95%, Protein G purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | HRP |
バックグラウンド: | Unwinds double-stranded DNA and RNA in a 3' to 5' direction. Alteration of secondary structure may subsequently influence interactions with proteins or other nucleic acid,. Functions as a transcriptional activator. Component of the CRD-mediated complex that promotes MYC mRNA stability. Involved with LARP6 in the stabilization of type I collagen mRNAs for CO1A1 and CO1A2. As component of a large PER complex is involved in the inhibition of 3' transcriptional termination of circadian target genes such as PER1 and NR1D1 and the control of the circadian rhythms. Positively regulates HIV-1 LTR-directed gene expression. |
シノニム: | ATP-dependent RNA helicase A (EC 3.6.4.13) (DEAH box protein 9) (DExH-box helicase 9) (Leukophysin) (LKP) (Nuclear DNA helicase II) (NDH II) (RNA helicase A), DHX9, DDX9 LKP NDH2 |
UniProt Protein Function: | DDX9: a helicase that unwinds double-stranded DNA and RNA in a 3' to 5' direction. Interacts with the RNA-induced silencing complex (RISC) in human cells and functions in RISC loading. Generates multiple secondary structures that influence RNA-binding proteins. Has a dsRNA binding motif at the N-terminus, RGG-box at the carboxyl terminus, and a bidirectional nuclear transport domain of 110 amino acids at the carboxyl terminus. May play a role in X-linked gene expression. |
UniProt Protein Details: | Protein type:Nuclear receptor co-regulator; Spliceosome; Nucleolus; Helicase; RNA splicing; EC 3.6.4.13; RNA-binding; RNA processing Chromosomal Location of Human Ortholog: 1q25 Cellular Component: nucleoplasm; centrosome; membrane; cytoplasm; nucleolus; nucleus; ribonucleoprotein complex; cytosol Molecular Function:ATP-dependent DNA helicase activity; protein binding; DNA binding; ATP-dependent RNA helicase activity; ATP binding; RNA helicase activity Biological Process: osteoblast differentiation; circadian rhythm; RNA processing; nuclear mRNA splicing, via spliceosome; RNA splicing; positive regulation of interferon type I production; innate immune response; gene expression; DNA duplex unwinding |
NCBI Summary: | This gene encodes a member of the DEAH-containing family of RNA helicases. The encoded protein is an enzyme that catalyzes the ATP-dependent unwinding of double-stranded RNA and DNA-RNA complexes. This protein localizes to both the nucleus and the cytoplasm and functions as a transcriptional regulator. This protein may also be involved in the expression and nuclear export of retroviral RNAs. Alternate splicing results in multiple transcript variants. Pseudogenes of this gene are found on chromosomes 11 and 13.[provided by RefSeq, Feb 2010] |
UniProt Code: | Q08211 |
NCBI GenInfo Identifier: | 116241330 |
NCBI Gene ID: | 1660 |
NCBI Accession: | Q08211.4 |
UniProt Related Accession: | Q08211 |
Molecular Weight: | 141kDa |
NCBI Full Name: | ATP-dependent RNA helicase A |
NCBI Synonym Full Names: | DExH-box helicase 9 |
NCBI Official Symbol: | DHX9 |
NCBI Official Synonym Symbols: | LKP; RHA; DDX9; NDH2; NDHII |
NCBI Protein Information: | ATP-dependent RNA helicase A |
UniProt Protein Name: | ATP-dependent RNA helicase A |
UniProt Synonym Protein Names: | DEAH box protein 9; Leukophysin; LKP; Nuclear DNA helicase II; NDH II |
UniProt Gene Name: | DHX9 |
UniProt Entry Name: | DHX9_HUMAN |