DHPS Antibody (PACO54738)
- SKU:
- PACO54738
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
抗体名: | DHPS Antibody (PACO54738) |
抗体コード: | PACO54738 |
サイズ: | 50ug |
宿主種: | Rabbit |
申し込み: | ELISA, IHC |
推奨される希釈: | ELISA:1:2000-1:10000, IHC:1:20-1:200 |
反応性: | Human |
免疫原: | Recombinant Human Deoxyhypusine synthase protein (1-94AA) |
憲法: | Liquid |
ストレージバッファ: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
精製方法: | >95%, Protein G purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Non-conjugated |
![]() | Immunohistochemistry of paraffin-embedded human testis tissue using PACO54738 at dilution of 1:100. |
バックグラウンド: | Catalyzes the NAD-dependent oxidative cleavage of spermidine and the subsequent transfer of the butylamine moiety of spermidine to the epsilon-amino group of a specific lysine residue of the eIF-5A precursor protein to form the intermediate deoxyhypusine residue. |
シノニム: | Deoxyhypusine synthase (DHS) (EC 2.5.1.46), DHPS, DS |
UniProt Protein Function: | DHPS: Catalyzes the NAD-dependent oxidative cleavage of spermidine and the subsequent transfer of the butylamine moiety of spermidine to the epsilon-amino group of a specific lysine residue of the eIF-5A precursor protein to form the intermediate deoxyhypusine residue. Belongs to the deoxyhypusine synthase family. 2 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:Cell cycle regulation; EC 2.5.1.46; Transferase Chromosomal Location of Human Ortholog: 19p13.2 Cellular Component: cytosol Molecular Function:deoxyhypusine synthase activity; protein binding Biological Process: hypusine biosynthetic process from peptidyl-lysine; positive regulation of cell proliferation; translation |
NCBI Summary: | This gene encodes a protein that is required for the formation of hypusine, a unique amino acid formed by the posttranslational modification of only one protein, eukaryotic translation initiation factor 5A. The encoded protein catalyzes the first step in hypusine formation by transferring the butylamine moiety of spermidine to a specific lysine residue of the eukaryotic translation initiation factor 5A precursor, forming an intermediate deoxyhypusine residue. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, May 2011] |
UniProt Code: | P49366 |
NCBI GenInfo Identifier: | 1352267 |
NCBI Gene ID: | 1725 |
NCBI Accession: | P49366.1 |
UniProt Secondary Accession: | P49366,Q13184, Q13276, Q9UDG0, A8K688, M0R1I5, |
UniProt Related Accession: | P49366 |
Molecular Weight: | 36,583 Da |
NCBI Full Name: | Deoxyhypusine synthase |
NCBI Synonym Full Names: | deoxyhypusine synthase |
NCBI Official Symbol: | DHPS |
NCBI Official Synonym Symbols: | DS; DHS; MIG13 |
NCBI Protein Information: | deoxyhypusine synthase |
UniProt Protein Name: | Deoxyhypusine synthase |
UniProt Gene Name: | DHPS |
UniProt Entry Name: | DHYS_HUMAN |