DGKG Antibody, HRP conjugated (PACO26226)
- SKU:
- PACO26226
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Antibody type:
- Polyclonal
- Conjugation:
- HRP
Frequently bought together:
Description
抗体名: | DGKG Antibody, HRP conjugated (PACO26226) |
抗体コード: | PACO26226 |
サイズ: | 50ug |
宿主種: | Rabbit |
申し込み: | ELISA |
推奨される希釈: | |
反応性: | Human |
免疫原: | Recombinant Human Diacylglycerol kinase γ protein (1-255AA) |
憲法: | Liquid |
ストレージバッファ: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
精製方法: | >95%, Protein G purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | HRP |
バックグラウンド: | Reverses the normal flow of glycerolipid biosynthesis by phosphorylating diacylglycerol back to phosphatidic acid, |
シノニム: | Diacylglycerol kinase γ (DAG kinase gamma) (EC 2.7.1.107) (Diglyceride kinase gamma) (DGK-gamma), DGKG, DAGK3 |
UniProt Protein Function: | DGKG: Reverses the normal flow of glycerolipid biosynthesis by phosphorylating diacylglycerol back to phosphatidic acid. Belongs to the eukaryotic diacylglycerol kinase family. 3 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:EC 2.7.1.107; Lipid Metabolism - glycerolipid; Motility/polarity/chemotaxis; Lipid Metabolism - glycerophospholipid; Kinase, lipid Chromosomal Location of Human Ortholog: 3q27.2-q27.3 Cellular Component: cytoplasm; plasma membrane Molecular Function:ATP binding; calcium ion binding; diacylglycerol kinase activity Biological Process: blood coagulation; neuron development; phosphorylation; platelet activation; protein kinase C activation; signal transduction |
NCBI Summary: | This gene encodes an enzyme that is a member of the type I subfamily of diacylglycerol kinases, which are involved in lipid metabolism. These enzymes generate phosphatidic acid by catalyzing the phosphorylation of diacylglycerol, a fundamental lipid second messenger that activates numerous proteins, including protein kinase C isoforms, Ras guanyl nucleotide-releasing proteins and some transient receptor potential channels. Diacylglycerol kinase gamma has been implicated in cell cycle regulation and in the negative regulation of macrophage differentiation in leukemia cells. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] |
UniProt Code: | P49619 |
NCBI GenInfo Identifier: | 124256474 |
NCBI Gene ID: | 1608 |
NCBI Accession: | NP_001074213.1 |
UniProt Secondary Accession: | P49619,Q2M1H4, Q5FWG1, B2RAH4, |
UniProt Related Accession: | P49619 |
Molecular Weight: | 44.9 kDa |
NCBI Full Name: | diacylglycerol kinase gamma isoform 2 |
NCBI Synonym Full Names: | diacylglycerol kinase gamma |
NCBI Official Symbol: | DGKG |
NCBI Official Synonym Symbols: | DAGK3; DGK-GAMMA |
NCBI Protein Information: | diacylglycerol kinase gamma |
UniProt Protein Name: | Diacylglycerol kinase gamma |
UniProt Synonym Protein Names: | Diglyceride kinase gamma; DGK-gamma |
Protein Family: | Diacylglycerol kinase |
UniProt Gene Name: | DGKG |
UniProt Entry Name: | DGKG_HUMAN |