DENND5A Antibody, HRP conjugated (PACO37003)
- SKU:
- PACO37003
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Antibody type:
- Polyclonal
- Conjugation:
- HRP
Frequently bought together:
Description
抗体名: | DENND5A Antibody, HRP conjugated (PACO37003) |
抗体コード: | PACO37003 |
サイズ: | 50ug |
宿主種: | Rabbit |
申し込み: | ELISA |
推奨される希釈: | |
反応性: | Human |
免疫原: | Recombinant Human DENN domain-containing protein 5A protein (1-300AA) |
憲法: | Liquid |
ストレージバッファ: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
精製方法: | >95%, Protein G purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | HRP |
バックグラウンド: | Guanine nucleotide exchange factor (GEF) which may activate RAB6A and RAB39A and/or RAB39B. Promotes the exchange of GDP to GTP, converting inactive GDP-bound Rab proteins into their active GTP-bound form. |
シノニム: | DENN domain-containing protein 5A (Rab6-interacting protein 1) (Rab6IP1), DENND5A, KIAA1091 RAB6IP1 |
UniProt Protein Function: | Guanine nucleotide exchange factor (GEF) which may activate RAB6A and RAB39A and/or RAB39B. Promotes the exchange of GDP to GTP, converting inactive GDP-bound Rab proteins into their active GTP-bound form. Involved in the negative regulation of neurite outgrowth. |
NCBI Summary: | This gene encodes a DENN-domain-containing protein that functions as a RAB-activating guanine nucleotide exchange factor (GEF). This protein catalyzes the conversion of GDP to GTP and thereby converts inactive GDP-bound Rab proteins into their active GTP-bound form. The encoded protein is recruited by RAB6 onto Golgi membranes and is therefore referred to as RAB6-interacting protein 1. This protein binds with RAB39 as well. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Mutations in this gene are associated with early infantile epileptic encephalopathy-49. [provided by RefSeq, Feb 2017] |
UniProt Code: | Q6IQ26 |
NCBI GenInfo Identifier: | 343098489 |
NCBI Gene ID: | 23258 |
NCBI Accession: | NP_001230183.1 |
UniProt Secondary Accession: | Q6IQ26,Q96GN3, Q9H6U7, Q9UFV0, Q9UPR1, B4DJ15, E9PS91 |
UniProt Related Accession: | Q6IQ26 |
Molecular Weight: | 141 |
NCBI Full Name: | DENN domain-containing protein 5A isoform 2 |
NCBI Synonym Full Names: | DENN domain containing 5A |
NCBI Official Symbol: | DENND5A |
NCBI Official Synonym Symbols: | EIEE49; RAB6IP1 |
NCBI Protein Information: | DENN domain-containing protein 5A |
UniProt Protein Name: | DENN domain-containing protein 5A |
UniProt Synonym Protein Names: | Rab6-interacting protein 1; Rab6IP1 |
UniProt Gene Name: | DENND5A |