DEK Antibody (PACO08805)
- SKU:
- PACO08805
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Application:
- IHC
- Application:
- IF
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
抗体名: | DEK Antibody (PACO08805) |
抗体コード: | PACO08805 |
サイズ: | 50ul |
宿主種: | Rabbit |
申し込み: | ELISA, WB, IHC, IF |
推奨される希釈: | |
反応性: | Human, Mouse, Rat |
免疫原: | Human DEK |
憲法: | Liquid |
ストレージバッファ: | PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles. |
精製方法: | Antigen Affinity purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Non-conjugated |
シノニム: | DEK oncogene;DEK;D6S231E ; |
UniProt Protein Function: | DEK: a ubiquitous protein with a SAP domain, which is found in a variety of nuclear proteins involved in transcription, DNA repair, RNA processing or apoptotic chromatin degradation. This protein binds to cruciform and superhelical DNA and induces positive supercoils into closed circular DNA and is also involved in splice site selection during mRNA processing. A chromosomal aberration involving DEK is found in a subset of acute myeloid leukemias (AML). |
UniProt Protein Details: | Protein type:Histone-binding; Oncoprotein; DNA-binding; DNA replication; RNA splicing Chromosomal Location of Human Ortholog: 6p22.3 Cellular Component: contractile fiber; nucleoplasm; nucleus Molecular Function:DNA binding; histone binding Biological Process: chromatin modification; positive regulation of gene expression, epigenetic; regulation of transcription from RNA polymerase II promoter; signal transduction; transcription from RNA polymerase II promoter; viral genome replication |
NCBI Summary: | This gene encodes a protein with one SAP domain. This protein binds to cruciform and superhelical DNA and induces positive supercoils into closed circular DNA, and is also involved in splice site selection during mRNA processing. Chromosomal aberrations involving this region, increased expression of this gene, and the presence of antibodies against this protein are all associated with various diseases. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2008] |
UniProt Code: | P35659 |
NCBI GenInfo Identifier: | 544150 |
NCBI Gene ID: | 7913 |
NCBI Accession: | P35659.1 |
UniProt Related Accession: | P35659 |
Molecular Weight: | |
NCBI Full Name: | Protein DEK |
NCBI Synonym Full Names: | DEK proto-oncogene |
NCBI Official Symbol: | DEK |
NCBI Official Synonym Symbols: | D6S231E |
NCBI Protein Information: | protein DEK |
UniProt Protein Name: | Protein DEK |
Protein Family: | Protein |
UniProt Gene Name: | DEK |
UniProt Entry Name: | DEK_HUMAN |