DEFA5 Antibody (PACO19276)
- SKU:
- PACO19276
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
抗体名: | DEFA5 Antibody (PACO19276) |
抗体コード: | PACO19276 |
サイズ: | 50ul |
宿主種: | Rabbit |
申し込み: | ELISA, IHC |
推奨される希釈: | ELISA:1:1000-1:2000, IHC:1:25-1:100 |
反応性: | Human |
免疫原: | Synthetic peptide of human DEFA5 |
憲法: | Liquid |
ストレージバッファ: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
精製方法: | Antigen affinity purification |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Non-conjugated |
![]() | The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using PACO19276(DEFA5 Antibody) at dilution 1/15, on the right is treated with synthetic peptide. (Original magnification: x200). |
![]() | The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using PACO19276(DEFA5 Antibody) at dilution 1/15, on the right is treated with synthetic peptide. (Original magnification: x200). |
バックグラウンド: | Defensins are a family of microbicidal and cytotoxic peptides thought to be involved in host defense. They are abundant in the granules of neutrophils and also found in the epithelia of mucosal surfaces such as those of the intestine, respiratory tract, urinary tract, and vagina. Members of the defensin family are highly similar in protein sequence and distinguished by a conserved cysteine motif. Several of the α defensin genes appear to be clustered on chromosome 8. The protein encoded by this gene, defensin, α 5, is highly expressed in the secretory granules of Paneth cells of the ileum. |
シノニム: | defensin, α 5, Paneth cell-specific |
UniProt Protein Function: | Has antimicrobial activity against Gram-negative and Gram-positive bacteria. Defensins are thought to kill microbes by permeabilizing their plasma membrane. All DEFA5 peptides exert antimicrobial activities, but their potency is affected by peptide processing. |
NCBI Summary: | Defensins are a family of antimicrobial and cytotoxic peptides thought to be involved in host defense. They are abundant in the granules of neutrophils and also found in the epithelia of mucosal surfaces such as those of the intestine, respiratory tract, urinary tract, and vagina. Members of the defensin family are highly similar in protein sequence and distinguished by a conserved cysteine motif. Several of the alpha defensin genes appear to be clustered on chromosome 8. The protein encoded by this gene, defensin, alpha 5, is highly expressed in the secretory granules of Paneth cells of the ileum. [provided by RefSeq, Oct 2014] |
UniProt Code: | Q01523 |
NCBI GenInfo Identifier: | 399353 |
NCBI Gene ID: | 1670 |
NCBI Accession: | Q01523.1 |
UniProt Secondary Accession: | Q01523,Q3KNV2, A0JDY6, |
UniProt Related Accession: | Q01523 |
Molecular Weight: | 10,071 Da |
NCBI Full Name: | Defensin-5 |
NCBI Synonym Full Names: | defensin alpha 5 |
NCBI Official Symbol: | DEFA5 |
NCBI Official Synonym Symbols: | DEF5; HD-5 |
NCBI Protein Information: | defensin-5 |
UniProt Protein Name: | Defensin-5 |
UniProt Synonym Protein Names: | Defensin, alpha 5; HD5(20-94) |
UniProt Gene Name: | DEFA5 |
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