DDX43 Antibody (PACO16169)
- SKU:
- PACO16169
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
抗体名: | DDX43 Antibody (PACO16169) |
抗体コード: | PACO16169 |
サイズ: | 50ul |
宿主種: | Rabbit |
申し込み: | ELISA, WB, IHC |
推奨される希釈: | ELISA:1:2000-1:5000, WB:1:200-1:1000, IHC:1:50-1:200 |
反応性: | Human |
免疫原: | Fusion protein of human DDX43 |
憲法: | Liquid |
ストレージバッファ: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
精製方法: | Antigen affinity purification |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Non-conjugated |
![]() | The image on the left is immunohistochemistry of paraffin-embedded Human brain tissue using PACO16169(DDX43 Antibody) at dilution 1/40, on the right is treated with fusion protein. (Original magnification: x200). |
![]() | Gel: 8%SDS-PAGE, Lysate: 40 μg, Lane: HepG2 cells, Primary antibody: PACO16169(DDX43 Antibody) at dilution 1/200, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 3 minutes. |
![]() | The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using PACO16169(DDX43 Antibody) at dilution 1/40, on the right is treated with fusion protein. (Original magnification: x200). |
バックグラウンド: | DEAD-box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp, are putative RNA helicases implicated in several cellular processes involving modifications of RNA secondary structure and ribosome/spliceosome assembly. Based on their distribution patterns, some members of this family may be involved in embryogenesis, spermatogenesis and cellular growth and division. DDX43 (DEAD (Asp-Glu-Ala-Asp) box polypeptide 43), also known as CT13 or HAGE, is a 648 amino acid, protein that contains one KH domain, one helicase C-terminal domain and one helicase ATP-binding domain and belongs to the DEAD-box family. Expressed in testis and present at abnormally high levels in a variety of tumors, DDX43 is thought to function as an ATP-dependent RNA helicase that may play a role tumor transformation and metastasis. |
シノニム: | DEAD (Asp-Glu-Ala-Asp) box polypeptide 43 |
UniProt Protein Function: | DDX43: is an ATP-dependent RNA helicase in the DEAD-box family and displays tumor-specific expression. [provided by RefSeq, Jul 2008] |
UniProt Protein Details: | Protein type:Cancer Testis Antigen (CTA); EC 3.6.4.13; Helicase; RNA-binding Chromosomal Location of Human Ortholog: 6q13 Cellular Component: intracellular Molecular Function:ATP-dependent RNA helicase activity Biological Process: RNA secondary structure unwinding |
NCBI Summary: | The protein encoded by this gene is an ATP-dependent RNA helicase in the DEAD-box family and displays tumor-specific expression. [provided by RefSeq, Jul 2008] |
UniProt Code: | Q9NXZ2 |
NCBI GenInfo Identifier: | 222352149 |
NCBI Gene ID: | 55510 |
NCBI Accession: | NP_061135.2 |
UniProt Secondary Accession: | Q9NXZ2,Q6NXR1, B4E0C8, |
UniProt Related Accession: | Q9NXZ2 |
Molecular Weight: | 21,295 Da |
NCBI Full Name: | probable ATP-dependent RNA helicase DDX43 |
NCBI Synonym Full Names: | DEAD-box helicase 43 |
NCBI Official Symbol: | DDX43 |
NCBI Official Synonym Symbols: | CT13; HAGE |
NCBI Protein Information: | probable ATP-dependent RNA helicase DDX43 |
UniProt Protein Name: | Probable ATP-dependent RNA helicase DDX43 |
UniProt Synonym Protein Names: | Cancer/testis antigen 13; CT13; DEAD box protein 43; DEAD box protein HAGE; Helical antigen |
Protein Family: | Probable ATP-dependent RNA helicase |
UniProt Gene Name: | DDX43 |