DDHD2 Antibody, Biotin conjugated (PACO26184)
- SKU:
- PACO26184
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Antibody type:
- Polyclonal
- Conjugation:
- Biotin
Frequently bought together:
Description
抗体名: | DDHD2 Antibody, Biotin conjugated (PACO26184) |
抗体コード: | PACO26184 |
サイズ: | 50ug |
宿主種: | Rabbit |
申し込み: | ELISA |
推奨される希釈: | |
反応性: | Human |
免疫原: | Recombinant Human Phospholipase DDHD2 protein (361-650AA) |
憲法: | Liquid |
ストレージバッファ: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
精製方法: | >95%, Protein G purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Biotin |
バックグラウンド: | Phospholipase that hydrolyzes preferentially phosphatidic acid, including 1,2-dioleoyl-sn-phosphatidic acid, and phosphatidylethanolamine. Specifically binds to phosphatidylinositol 3-phosphate (PI(3)P), phosphatidylinositol 4-phosphate (PI(4)P), phosphatidylinositol 5-phosphate (PI(5)P) and possibly phosphatidylinositol 4,5-bisphosphate (PI(4,5)P2). May be involved in the maintenance of the endoplasmic reticulum and/or Golgi structures. May regulate the transport between Golgi apparatus and plasma membrane. |
シノニム: | Phospholipase DDHD2 (EC 3.1.1.-) (DDHD domain-containing protein 2) (KIAA0725p) (SAM, WWE and DDHD domain-containing protein 1), DDHD2, KIAA0725 SAMWD1 |
UniProt Protein Function: | DDHD2: Phospholipase that hydrolyzes preferentially phosphatidic acid and phosphatidylethanolamine. May be involved in the maintenance of the endoplasmic reticulum and/or Golgi structures. Belongs to the PA-PLA1 family. |
UniProt Protein Details: | Protein type:EC 3.1.1.-; Hydrolase Chromosomal Location of Human Ortholog: 8p11.23 Cellular Component: cytoplasm; cytosol; ER-Golgi intermediate compartment; Golgi apparatus; microtubule organizing center Molecular Function:hydrolase activity; metal ion binding Biological Process: glycerophospholipid biosynthetic process; lipid catabolic process; phosphatidic acid biosynthetic process; phospholipid metabolic process Disease: Spastic Paraplegia 54, Autosomal Recessive |
NCBI Summary: | This gene encodes a phospholipase enzyme containing sterile-alpha-motif (SAM), WWE, and DDHD domains. This protein participates in membrane trafficking between the endoplastic reticulum and the Golgi body. Mutations in this gene can cause autosomal recessive spastic paraplegia 54. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2013] |
UniProt Code: | O94830 |
NCBI GenInfo Identifier: | 256017247 |
NCBI Gene ID: | 23259 |
NCBI Accession: | NP_001157704.1 |
UniProt Secondary Accession: | O94830,Q9H8X7, B3KWV2, B3KXB5, |
UniProt Related Accession: | O94830 |
Molecular Weight: | 37,682 Da |
NCBI Full Name: | phospholipase DDHD2 isoform 1 |
NCBI Synonym Full Names: | DDHD domain containing 2 |
NCBI Official Symbol: | DDHD2 |
NCBI Official Synonym Symbols: | SPG54; SAMWD1; iPLA(1)gamma |
NCBI Protein Information: | phospholipase DDHD2 |
UniProt Protein Name: | Phospholipase DDHD2 |
UniProt Synonym Protein Names: | DDHD domain-containing protein 2; KIAA0725p; SAM, WWE and DDHD domain-containing protein 1 |
Protein Family: | Phospholipase |
UniProt Gene Name: | DDHD2 |
UniProt Entry Name: | DDHD2_HUMAN |