DCN Antibody, HRP conjugated (PACO32833)
- SKU:
- PACO32833
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Antibody type:
- Polyclonal
- Conjugation:
- HRP
Description
抗体名: | DCN Antibody, HRP conjugated (PACO32833) |
抗体コード: | PACO32833 |
サイズ: | 50ug |
宿主種: | Rabbit |
申し込み: | ELISA |
推奨される希釈: | |
反応性: | Human |
免疫原: | Recombinant Human Decorin protein (20-359AA) |
憲法: | Liquid |
ストレージバッファ: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
精製方法: | >95%, Protein G purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | HRP |
バックグラウンド: | May affect the rate of fibrils formation. |
シノニム: | Decorin (Bone proteoglycan II) (PG-S2) (PG40), DCN, SLRR1B |
UniProt Protein Function: | DCN: May affect the rate of fibrils formation. Defects in DCN are the cause of congenital stromal corneal dystrophy (CSCD). Corneal dystrophies are inherited, bilateral, primary alterations of the cornea that are not associated with prior inflammation or secondary to systemic disease. Most show autosomal dominant inheritance. Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class I subfamily. 5 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:Secreted, signal peptide; Extracellular matrix; Secreted; Motility/polarity/chemotaxis Chromosomal Location of Human Ortholog: 12q21.33 Cellular Component: extracellular matrix; lysosomal lumen; proteinaceous extracellular matrix; extracellular space; Golgi lumen; extracellular region; collagen type VI Molecular Function:collagen binding; glycosaminoglycan binding; extracellular matrix binding; protein N-terminus binding Biological Process: extracellular matrix organization and biogenesis; skeletal muscle development; chondroitin sulfate biosynthetic process; glycosaminoglycan metabolic process; wound healing; response to lipopolysaccharide; pathogenesis; dermatan sulfate biosynthetic process; chondroitin sulfate metabolic process; extracellular matrix disassembly; organ morphogenesis; response to mechanical stimulus; chondroitin sulfate catabolic process; carbohydrate metabolic process; kidney development; peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan; aging; placenta development Disease: Corneal Dystrophy, Congenital Stromal |
NCBI Summary: | The protein encoded by this gene is a small cellular or pericellular matrix proteoglycan that is closely related in structure to biglycan protein. The encoded protein and biglycan are thought to be the result of a gene duplication. This protein is a component of connective tissue, binds to type I collagen fibrils, and plays a role in matrix assembly. It contains one attached glycosaminoglycan chain. This protein is capable of suppressing the growth of various tumor cell lines. There are multiple alternatively spliced transcript variants known for this gene. This gene is a candidate gene for Marfan syndrome. [provided by RefSeq, Jul 2008] |
UniProt Code: | P07585 |
NCBI GenInfo Identifier: | 129951 |
NCBI Gene ID: | 1634 |
NCBI Accession: | P07585.1 |
UniProt Secondary Accession: | P07585,Q9P0Z0, Q9P0Z1, Q9Y5N8, Q9Y5N9, |
UniProt Related Accession: | P07585 |
Molecular Weight: | 8,266 Da |
NCBI Full Name: | Decorin |
NCBI Synonym Full Names: | decorin |
NCBI Official Symbol: | DCN |
NCBI Official Synonym Symbols: | CSCD; PG40; PGII; PGS2; DSPG2; SLRR1B |
NCBI Protein Information: | decorin; PG-S2; bone proteoglycan II; decorin proteoglycan; proteoglycan core protein; small leucine-rich protein 1B; dermatan sulphate proteoglycans II |
UniProt Protein Name: | Decorin |
UniProt Synonym Protein Names: | Bone proteoglycan II; PG-S2; PG40 |
Protein Family: | Decorin |
UniProt Gene Name: | DCN |
UniProt Entry Name: | PGS2_HUMAN |