Dcn Antibody, HRP conjugated (PACO26156)
- SKU:
- PACO26156
- Product type:
- Antibody
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Antibody type:
- Polyclonal
- Conjugation:
- HRP
Frequently bought together:
Description
抗体名: | Dcn Antibody, HRP conjugated (PACO26156) |
抗体コード: | PACO26156 |
サイズ: | 50ug |
宿主種: | Rabbit |
申し込み: | ELISA |
推奨される希釈: | |
反応性: | Mouse |
免疫原: | Recombinant Mouse Decorin protein (35-354AA) |
憲法: | Liquid |
ストレージバッファ: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
精製方法: | >95%, Protein G purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | HRP |
バックグラウンド: | May affect the rate of fibrils formation. |
シノニム: | Decorin (Bone proteoglycan II) (PG-S2) (PG40), Dcn |
UniProt Protein Function: | DCN: May affect the rate of fibrils formation. Defects in DCN are the cause of congenital stromal corneal dystrophy (CSCD). Corneal dystrophies are inherited, bilateral, primary alterations of the cornea that are not associated with prior inflammation or secondary to systemic disease. Most show autosomal dominant inheritance. Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class I subfamily. 5 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:Secreted; Extracellular matrix; Secreted, signal peptide; Motility/polarity/chemotaxis Cellular Component: extracellular matrix; extracellular space; proteinaceous extracellular matrix; extracellular region; collagen type VI Molecular Function:collagen binding; glycosaminoglycan binding; extracellular matrix binding; protein N-terminus binding Biological Process: peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan |
NCBI Summary: | This gene encodes a member of the small leucine-rich proteoglycan (SLRP) family of proteins. The encoded preproprotein is proteolytically processed to generate a mature protein product, which is secreted into the extracellular space to regulate collagen fibril assembly. Homozygous knockout mice for this gene exhibit enhanced tumorigenesis in a liver cancer model, and defects in collagen fibrils, leading to weakened skin and tendons. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2015] |
UniProt Code: | P28654 |
NCBI GenInfo Identifier: | 129952 |
NCBI Gene ID: | 13179 |
NCBI Accession: | P28654.1 |
UniProt Related Accession: | P28654 |
Molecular Weight: | 39,809 Da |
NCBI Full Name: | Decorin |
NCBI Synonym Full Names: | decorin |
NCBI Official Symbol: | Dcn |
NCBI Official Synonym Symbols: | DC; PG40; PGII; PGS2; mDcn; DSPG2; SLRR1B |
NCBI Protein Information: | decorin; bone proteoglycan II |
UniProt Protein Name: | Decorin |
UniProt Synonym Protein Names: | Bone proteoglycan II; PG-S2; PG40 |
Protein Family: | Decorin |
UniProt Gene Name: | Dcn |
UniProt Entry Name: | PGS2_MOUSE |