DARS Antibody, HRP conjugated (PACO26138)
- SKU:
- PACO26138
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Antibody type:
- Polyclonal
- Conjugation:
- HRP
Frequently bought together:
Description
抗体名: | DARS Antibody, HRP conjugated (PACO26138) |
抗体コード: | PACO26138 |
サイズ: | 50ug |
宿主種: | Rabbit |
申し込み: | ELISA |
推奨される希釈: | |
反応性: | Human |
免疫原: | Recombinant Human Aspartate--tRNA ligase, cytoplasmic protein (1-300AA) |
憲法: | Liquid |
ストレージバッファ: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
精製方法: | >95%, Protein G purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | HRP |
バックグラウンド: | Catalyzes the specific attachment of an amino acid, to its cognate tRNA in a 2 step reaction: the amino acid, (AA) is first activated by ATP to form AA-AMP and then transferred to the acceptor end of the tRNA. |
シノニム: | Aspartate--tRNA ligase, cytoplasmic (EC 6.1.1.12) (Aspartyl-tRNA synthetase) (AspRS) (Cell proliferation-inducing gene 40 protein), DARS |
UniProt Protein Function: | DARS: Catalyzes the specific attachment of an amino acid to its cognate tRNA in a 2 step reaction: the amino acid (AA) is first activated by ATP to form AA-AMP and then transferred to the acceptor end of the tRNA. Belongs to the class-II aminoacyl-tRNA synthetase family. |
UniProt Protein Details: | Protein type:Translation; EC 6.1.1.12; Ligase Chromosomal Location of Human Ortholog: 2q21.3 Cellular Component: membrane; cytoplasm; cytosol Molecular Function:protein binding; aspartate-tRNA ligase activity; ATP binding; aminoacylase activity Biological Process: tRNA aminoacylation for protein translation; translation; protein complex assembly; gene expression; aspartyl-tRNA aminoacylation Disease: Hypomyelination With Brainstem And Spinal Cord Involvement And Leg Spasticity |
NCBI Summary: | This gene encodes a member of a multienzyme complex that functions in mediating the attachment of amino acids to their cognate tRNAs. The encoded protein ligates L-aspartate to tRNA(Asp). Mutations in this gene have been found in patients showing hypomyelination with brainstem and spinal cord involvement and leg spasticity. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2014] |
UniProt Code: | P14868 |
NCBI GenInfo Identifier: | 20178330 |
NCBI Gene ID: | 1615 |
NCBI Accession: | P14868.2 |
UniProt Secondary Accession: | P14868,Q2TNI3, Q32Q69, Q53HV4, Q53YC5, Q68CR9, Q9BW52 A8K3J2, D3DP77, |
UniProt Related Accession: | P14868 |
Molecular Weight: | 501 |
NCBI Full Name: | Aspartate--tRNA ligase, cytoplasmic |
NCBI Synonym Full Names: | aspartyl-tRNA synthetase |
NCBI Official Symbol: | DARS |
NCBI Official Synonym Symbols: | HBSL; aspRS |
NCBI Protein Information: | aspartate--tRNA ligase, cytoplasmic; aspartate tRNA ligase 1, cytoplasmic; aspartyl-tRNA synthetase, cytoplasmic; cell proliferation-inducing gene 40 protein |
UniProt Protein Name: | Aspartate--tRNA ligase, cytoplasmic |
UniProt Synonym Protein Names: | Aspartyl-tRNA synthetase; AspRS; Cell proliferation-inducing gene 40 protein |
UniProt Gene Name: | DARS |
UniProt Entry Name: | SYDC_HUMAN |