CYP3A7 Antibody, HRP conjugated (PACO26106)
- SKU:
- PACO26106
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Antibody type:
- Polyclonal
- Conjugation:
- HRP
Frequently bought together:
Description
抗体名: | CYP3A7 Antibody, HRP conjugated (PACO26106) |
抗体コード: | PACO26106 |
サイズ: | 50ug |
宿主種: | Rabbit |
申し込み: | ELISA |
推奨される希釈: | |
反応性: | Human |
免疫原: | Recombinant Human Cytochrome P450 3A7 protein (1-200AA) |
憲法: | Liquid |
ストレージバッファ: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
精製方法: | >95%, Protein G purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | HRP |
バックグラウンド: | Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acid, , and xenobiotics. |
シノニム: | Cytochrome P450 3A7 (EC 1.14.14.1) (CYPIIIA7) (Cytochrome P450-HFLA), CYP3A7 |
UniProt Protein Function: | CYP3A7: Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics. Belongs to the cytochrome P450 family. |
UniProt Protein Details: | Protein type:Xenobiotic Metabolism - metabolism by cytochrome P450; Oxidoreductase; Xenobiotic Metabolism - drug metabolism - cytochrome P450; Lipid Metabolism - linoleic acid; Xenobiotic Metabolism - drug metabolism - other enzymes; Cofactor and Vitamin Metabolism - retinol; EC 1.14.14.1 Chromosomal Location of Human Ortholog: 7q22.1 Cellular Component: endoplasmic reticulum membrane Molecular Function:iron ion binding; heme binding; oxygen binding; monooxygenase activity Biological Process: xenobiotic metabolic process |
NCBI Summary: | This gene encodes a member of the cytochrome P450 superfamily of enzymes, which participate in drug metabolism and the synthesis of cholesterol, steroids and other lipids. This enzyme hydroxylates testosterone and dehydroepiandrosterone 3-sulphate, which is involved in the formation of estriol during pregnancy. This gene is part of a cluster of related genes on chromosome 7q21.1. Naturally-occurring readthrough transcription occurs between this gene and the downstream CYP3A51P pseudogene and is represented by GeneID:100861540. [provided by RefSeq, Jan 2015] |
UniProt Code: | P24462 |
NCBI GenInfo Identifier: | 608788370 |
NCBI Gene ID: | 1551 |
NCBI Accession: | NP_000756.3 |
UniProt Secondary Accession: | P24462,Q9H241, A4D288, |
UniProt Related Accession: | P24462 |
Molecular Weight: | 61,547 Da |
NCBI Full Name: | cytochrome P450 3A7 |
NCBI Synonym Full Names: | cytochrome P450, family 3, subfamily A, polypeptide 7 |
NCBI Official Symbol: | CYP3A7 |
NCBI Official Synonym Symbols: | CP37; CYPIIIA7; P450-HFLA; P-450111A7; P-450(HFL33) |
NCBI Protein Information: | cytochrome P450 3A7 |
UniProt Protein Name: | Cytochrome P450 3A7 |
UniProt Synonym Protein Names: | CYPIIIA7; Cytochrome P450-HFLA |
Protein Family: | Cytochrome |
UniProt Gene Name: | CYP3A7 |
UniProt Entry Name: | CP3A7_HUMAN |