CYP3A5 Antibody (PACO08720)
- SKU:
- PACO08720
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
抗体名: | CYP3A5 Antibody (PACO08720) |
抗体コード: | PACO08720 |
サイズ: | 50ul |
宿主種: | Rabbit |
申し込み: | ELISA, WB, IHC |
推奨される希釈: | |
反応性: | Human |
免疫原: | Human CYP3A5 |
憲法: | Liquid |
ストレージバッファ: | PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles. |
精製方法: | Antigen Affinity Purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Non-conjugated |
シノニム: | cytochrome P450, family 3, subfamily A, polypeptide 5;CYP3A5;CP35;P450PCN3;PCN3 ; |
UniProt Protein Function: | CYP3A5: Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics. Belongs to the cytochrome P450 family. 2 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:Xenobiotic Metabolism - drug metabolism - other enzymes; EC 1.14.14.1; Oxidoreductase; Cofactor and Vitamin Metabolism - retinol; Lipid Metabolism - linoleic acid; Xenobiotic Metabolism - drug metabolism - cytochrome P450; Xenobiotic Metabolism - metabolism by cytochrome P450 Chromosomal Location of Human Ortholog: 7q21.1 Cellular Component: endoplasmic reticulum membrane; intracellular membrane-bound organelle Molecular Function:monooxygenase activity; oxidoreductase activity; oxygen binding Biological Process: alkaloid catabolic process; drug catabolic process; steroid metabolic process; xenobiotic metabolic process Disease: Hypertension, Essential |
NCBI Summary: | This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. The encoded protein metabolizes drugs as well as the steroid hormones testosterone and progesterone. This gene is part of a cluster of cytochrome P450 genes on chromosome 7q21.1. Two pseudogenes of this gene have been identified within this cluster on chromosome 7. Expression of this gene is widely variable among populations, and a single nucleotide polymorphism that affects transcript splicing has been associated with susceptibility to hypertensions. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2014] |
UniProt Code: | P20815 |
NCBI GenInfo Identifier: | 117157 |
NCBI Gene ID: | 1577 |
NCBI Accession: | P20815.1 |
UniProt Secondary Accession: | P20815,Q53WY8, Q75MV0, Q9HB56, A4D289, B7Z5I7, |
UniProt Related Accession: | P20815 |
Molecular Weight: | 15,846 Da |
NCBI Full Name: | Cytochrome P450 3A5 |
NCBI Synonym Full Names: | cytochrome P450 family 3 subfamily A member 5 |
NCBI Official Symbol: | CYP3A5 |
NCBI Official Synonym Symbols: | CP35; PCN3; CYPIIIA5; P450PCN3 |
NCBI Protein Information: | cytochrome P450 3A5 |
UniProt Protein Name: | Cytochrome P450 3A5 |
UniProt Synonym Protein Names: | CYPIIIA5; Cytochrome P450 HLp2; Cytochrome P450-PCN3 |
UniProt Gene Name: | CYP3A5 |
UniProt Entry Name: | CP3A5_HUMAN |