CYP2F1 Antibody (PACO08715)
- SKU:
- PACO08715
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Description
抗体名: | CYP2F1 Antibody (PACO08715) |
抗体コード: | PACO08715 |
サイズ: | 50ul |
宿主種: | Rabbit |
申し込み: | ELISA, WB |
推奨される希釈: | |
反応性: | Human, Mouse, Rat |
免疫原: | Human CYP2F1 |
憲法: | Liquid |
ストレージバッファ: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles. |
精製方法: | Antigen Affinity purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Non-conjugated |
シノニム: | cytochrome P450, family 2, subfamily F, polypeptide 1;CYP2F1;C2F1;CYP2F;MGC126121 ; |
UniProt Protein Function: | CYP2F2: May be involved in the metabolism of various pneumotoxicants including naphthalene. Is able to dealkylate ethoxycoumarin, propoxycoumarin, and pentoxyresorufin but possesses no activity toward ethoxyresorufin and only trace dearylation activity toward benzyloxyresorufin. Bioactivates 3- methylindole (3MI) by dehydrogenation to the putative electrophile 3-methylene-indolenine. Belongs to the cytochrome P450 family. |
UniProt Protein Details: | Protein type:Xenobiotic Metabolism - metabolism by cytochrome P450; EC 1.14.14.1; Oxidoreductase Chromosomal Location of Human Ortholog: 19q13.2 Cellular Component: endoplasmic reticulum membrane; intracellular membrane-bound organelle; cytoplasm Molecular Function:iron ion binding; heme binding; oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen; arachidonic acid epoxygenase activity; steroid hydroxylase activity; oxygen binding; monooxygenase activity Biological Process: response to toxin; xenobiotic metabolic process; exogenous drug catabolic process; trichloroethylene metabolic process; epoxygenase P450 pathway; naphthalene metabolic process |
NCBI Summary: | This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and is known to dehydrogenate 3-methylindole, an endogenous toxin derived from the fermentation of tryptophan, as well as xenobiotic substrates such as naphthalene and ethoxycoumarin. This gene is part of a large cluster of cytochrome P450 genes from the CYP2A, CYP2B and CYP2F subfamilies on chromosome 19q. [provided by RefSeq, Jul 2008] |
UniProt Code: | P24903 |
NCBI GenInfo Identifier: | 259016202 |
NCBI Gene ID: | 1572 |
NCBI Accession: | P24903.2 |
UniProt Related Accession: | P24903 |
Molecular Weight: | |
NCBI Full Name: | Cytochrome P450 2F1 |
NCBI Synonym Full Names: | cytochrome P450 family 2 subfamily F member 1 |
NCBI Official Symbol: | CYP2F1 |
NCBI Official Synonym Symbols: | C2F1; CYP2F; CYPIIF1 |
NCBI Protein Information: | cytochrome P450 2F1 |
UniProt Protein Name: | Cytochrome P450 2F1 |
UniProt Synonym Protein Names: | CYPIIF1 |
UniProt Gene Name: | CYP2F1 |
UniProt Entry Name: | CP2F1_HUMAN |