CXCR1 Antibody (PACO07416)
- SKU:
- PACO07416
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
抗体名: | CXCR1 Antibody (PACO07416) |
抗体コード: | PACO07416 |
サイズ: | 50ug |
宿主種: | Rabbit |
申し込み: | ELISA, IHC |
推奨される希釈: | ELISA:1:10000-1:20000, IHC-p:1:50-1:300 |
反応性: | Human |
免疫原: | Synthetic peptide from human protein at AA range: 1-50 |
憲法: | Liquid |
ストレージバッファ: | PBS, pH 7.4, containing 0.02% sodium azide as Preservative and 50% Glycerol. |
精製方法: | The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen. |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Non-conjugated |
Immunohistochemical analysis of paraffin-embedded Human-liver-cancer, antibody was diluted at 1:100. | |
Immunohistochemical analysis of paraffin-embedded Human-placenta, antibody was diluted at 1:100. | |
Immunohistochemical analysis of paraffin-embedded Human-liver-cancer, antibody was diluted at 1:100. |
シノニム: | C-X-C chemokine receptor type 1 (CXC-R1) (CXCR-1) (CDw128a) (High affinity interleukin-8 receptor A) (IL-8R A) (IL-8 receptor type 1) (CD antigen CD181) |
UniProt Protein Function: | IL8RA: Receptor to interleukin-8, which is a powerful neutrophils chemotactic factor. Binding of IL-8 to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activate a phosphatidylinositol-calcium second messenger system. This receptor binds to IL-8 with a high affinity and to MGSA (GRO) with a low affinity. Belongs to the G-protein coupled receptor 1 family. |
UniProt Protein Details: | Protein type:Membrane protein, multi-pass; GPCR, family 1; Membrane protein, integral; Receptor, GPCR; Receptor, cytokine Chromosomal Location of Human Ortholog: 2q35 Cellular Component: membrane; plasma membrane; integral to membrane Molecular Function:G-protein coupled receptor activity; interleukin-8 receptor activity; chemokine receptor activity; interleukin-8 binding Biological Process: G-protein coupled receptor protein signaling pathway; cell surface receptor linked signal transduction; receptor internalization; dendritic cell chemotaxis; chemotaxis; inflammatory response Disease: Human Immunodeficiency Virus Type 1, Susceptibility To |
NCBI Summary: | The protein encoded by this gene is a member of the G-protein-coupled receptor family. This protein is a receptor for interleukin 8 (IL8). It binds to IL8 with high affinity, and transduces the signal through a G-protein activated second messenger system. Knockout studies in mice suggested that this protein inhibits embryonic oligodendrocyte precursor migration in developing spinal cord. This gene, IL8RB, a gene encoding another high affinity IL8 receptor, as well as IL8RBP, a pseudogene of IL8RB, form a gene cluster in a region mapped to chromosome 2q33-q36. [provided by RefSeq, Jul 2008] |
UniProt Code: | P25024 |
NCBI GenInfo Identifier: | 108936015 |
NCBI Gene ID: | 3577 |
NCBI Accession: | P25024.2 |
UniProt Secondary Accession: | P25024,Q2YEF8, Q2YEG4, Q2YEG5, Q2YEG7, Q2YEG8, Q53R18 Q6IN95, Q8N6T6, Q9P2T8, Q9P2T9, B2R6Q3, |
UniProt Related Accession: | P25024 |
Molecular Weight: | 39,791 Da |
NCBI Full Name: | C-X-C chemokine receptor type 1 |
NCBI Synonym Full Names: | chemokine (C-X-C motif) receptor 1 |
NCBI Official Symbol: | CXCR1 |
NCBI Official Synonym Symbols: | C-C; CD128; CD181; CKR-1; IL8R1; IL8RA; CMKAR1; IL8RBA; CDw128a; C-C-CKR-1 |
NCBI Protein Information: | C-X-C chemokine receptor type 1; CXC-R1; CXCR-1; IL-8R A; IL-8 receptor type 1; interleukin 8 receptor, alpha; interleukin-8 receptor type 1; interleukin-8 receptor type A; high affinity interleukin-8 receptor A |
UniProt Protein Name: | C-X-C chemokine receptor type 1 |
UniProt Synonym Protein Names: | CDw128a; High affinity interleukin-8 receptor A; IL-8R A; IL-8 receptor type 1; CD_antigen: CD181 |
Protein Family: | C-X-C chemokine receptor |
UniProt Gene Name: | CXCR1 |
UniProt Entry Name: | CXCR1_HUMAN |
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