CXCL3 Antibody (PACO14455)
- SKU:
- PACO14455
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
抗体名: | CXCL3 Antibody (PACO14455) |
抗体コード: | PACO14455 |
サイズ: | 50ul |
宿主種: | Rabbit |
申し込み: | ELISA, IHC |
推奨される希釈: | ELISA:1:1000-1:2000, IHC:1:15-1:50 |
反応性: | Human |
免疫原: | Fusion protein of human CXCL3 |
憲法: | Liquid |
ストレージバッファ: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
精製方法: | Antigen affinity purification |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Non-conjugated |
The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using PACO14455(CXCL3 Antibody) at dilution 1/25, on the right is treated with fusion protein. (Original magnification: x200). | |
The image on the left is immunohistochemistry of paraffin-embedded Human ovarian cancer tissue using PACO14455(CXCL3 Antibody) at dilution 1/25, on the right is treated with fusion protein. (Original magnification: x200). |
バックグラウンド: | Chemokine (C-X-C motif) ligand 3 (CXCL3) is a small cytokine belonging to the CXC chemokine family that is also known as GRO3 oncogene (GRO3), GRO protein γ (GROg) and macrophage inflammatory protein-2-β (MIP2b). CXCL3 controls migration and adhesion of monocytes and mediates its effects on its target cell by interacting with a cell surface chemokine receptor called CXCR2. More recently, it has been shown that Cxcl3 regulates cell autonomously the migration of the precursors of cerebellar granule neurons toward the internal layers of cerebellum, during the morphogenesis of cerebellum. |
シノニム: | chemokine (C-X-C motif) ligand 3 |
UniProt Protein Function: | CXCL3: Ligand for CXCR2. Has chemotactic activity for neutrophils. May play a role in inflammation and exert its effects on endothelial cells in an autocrine fashion. In vitro, the processed form GRO-gamma(5-73) shows a fivefold higher chemotactic activity for neutrophilic granulocytes. Belongs to the intercrine alpha (chemokine CxC) family. |
UniProt Protein Details: | Protein type:Motility/polarity/chemotaxis; Secreted; Secreted, signal peptide Chromosomal Location of Human Ortholog: 4q21 Cellular Component: extracellular space; extracellular region Molecular Function:chemokine activity; CXCR chemokine receptor binding Biological Process: G-protein coupled receptor protein signaling pathway; neutrophil chemotaxis; response to lipopolysaccharide; positive regulation of leukocyte chemotaxis; immune response; inflammatory response; regulation of cell proliferation |
NCBI Summary: | This antimicrobial gene encodes a member of the CXC subfamily of chemokines. The encoded protein is a secreted growth factor that signals through the G-protein coupled receptor, CXC receptor 2. This protein plays a role in inflammation and as a chemoattractant for neutrophils. [provided by RefSeq, Sep 2014] |
UniProt Code: | P19876 |
NCBI GenInfo Identifier: | 127086 |
NCBI Gene ID: | 2921 |
NCBI Accession: | P19876.1 |
UniProt Secondary Accession: | P19876,Q4W5H9, |
UniProt Related Accession: | P19876 |
Molecular Weight: | 11,342 Da |
NCBI Full Name: | C-X-C motif chemokine 3 |
NCBI Synonym Full Names: | chemokine (C-X-C motif) ligand 3 |
NCBI Official Symbol: | CXCL3 |
NCBI Official Synonym Symbols: | GRO3; GROg; MIP2B; SCYB3; MIP-2b; CINC-2b |
NCBI Protein Information: | C-X-C motif chemokine 3; GRO-gamma; MIP2-beta; MGSA gamma; GRO3 oncogene; GRO-gamma(1-73); growth-regulated protein gamma; macrophage inflammatory protein 2-beta; melanoma growth stimulatory activity gamma |
UniProt Protein Name: | C-X-C motif chemokine 3 |
UniProt Synonym Protein Names: | GRO-gamma(1-73); Growth-regulated protein gamma; GRO-gamma; Macrophage inflammatory protein 2-beta; MIP2-beta |
UniProt Gene Name: | CXCL3 |
UniProt Entry Name: | CXCL3_HUMAN |
Antibodies | ELISA Kits |
CXCL3 Antibody (PACO04000) | Human CXCL3 / GRO gamma ELISA Kit |
CXCL3 Antibody (PACO08690) | Human C-X-C motif chemokine 3 (CXCL3) ELISA Kit |
Secondary Antibody |
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
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