CUX1 Antibody, HRP conjugated (PACO58121)
- SKU:
- PACO58121
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Antibody type:
- Polyclonal
- Conjugation:
- HRP
Frequently bought together:
Description
抗体名: | CUX1 Antibody, HRP conjugated (PACO58121) |
抗体コード: | PACO58121 |
サイズ: | 50ug |
宿主種: | Rabbit |
申し込み: | ELISA |
推奨される希釈: | |
反応性: | Human |
免疫原: | Recombinant Human Protein CASP protein (50-210AA) |
憲法: | Liquid |
ストレージバッファ: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
精製方法: | >95%, Protein G purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | HRP |
バックグラウンド: | May be involved in intra-Golgi retrograde transport. |
シノニム: | Protein CASP, CUX1, CUTL1 |
UniProt Protein Function: | CUTL1 iso1: Probably has a broad role in mammalian development as a repressor of developmentally regulated gene expression. May act by preventing binding of positively-activing CCAAT factors to promoters. Component of nf-munr repressor; binds to the matrix attachment regions (MARs) (5' and 3') of the immunoglobulin heavy chain enhancer. Represses T-cell receptor (TCR) beta enhancer function by binding to MARbeta, an ATC-rich DNA sequence located upstream of the TCR beta enhancer. Belongs to the CUT homeobox family. 8 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:Transcription factor; Membrane protein, integral; DNA-binding Chromosomal Location of Human Ortholog: 7q22.1 Cellular Component: cytosol; Golgi apparatus; nucleoplasm; nucleus Molecular Function:protein-tyrosine kinase activity; sequence-specific DNA binding Biological Process: multicellular organismal development; negative regulation of transcription from RNA polymerase II promoter; positive regulation of dendrite morphogenesis; regulation of transcription from RNA polymerase II promoter |
NCBI Summary: | The protein encoded by this gene is a member of the homeodomain family of DNA binding proteins. It may regulate gene expression, morphogenesis, and differentiation and it may also play a role in the cell cycle progession. Several alternatively spliced transcript variants encoding different isoforms have been identified.[provided by RefSeq, Feb 2011] |
UniProt Code: | Q13948 |
NCBI GenInfo Identifier: | 85681028 |
NCBI Gene ID: | 1523 |
NCBI Accession: | Q13948.2 |
UniProt Secondary Accession: | Q13948,Q53GU9, Q8TBS3, B3KWH3, B3KWH8, B4DZZ2, G3V1Z6 J3KPQ6, |
UniProt Related Accession: | Q13948,P39880 |
Molecular Weight: | 75,644 Da |
NCBI Full Name: | Protein CASP |
NCBI Synonym Full Names: | cut like homeobox 1 |
NCBI Official Symbol: | CUX1 |
NCBI Official Synonym Symbols: | CDP; CUX; p75; CASP; CDP1; COY1; Clox; p100; p110; p200; CUTL1; GOLIM6; CDP/Cut; Cux/CDP; Nbla10317 |
NCBI Protein Information: | protein CASP |
UniProt Protein Name: | Protein CASP |
Protein Family: | Homeobox protein |
UniProt Gene Name: | CUX1 |
UniProt Entry Name: | CASP_HUMAN |