CTSH Antibody (PACO08672)
- SKU:
- PACO08672
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Description
抗体名: | CTSH Antibody (PACO08672) |
抗体コード: | PACO08672 |
サイズ: | 50ul |
宿主種: | Rabbit |
申し込み: | ELISA, IHC |
推奨される希釈: | |
反応性: | Human, Mouse, Rat |
免疫原: | Human CTSH |
憲法: | Liquid |
ストレージバッファ: | PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles. |
精製方法: | Antigen Affinity Purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Non-conjugated |
シノニム: | cathepsin H;CTSH;ACC-4;ACC-5;CPSB;DKFZp686B24257;MGC1519;minichain ; |
UniProt Protein Function: | CTSH: Important for the overall degradation of proteins in lysosomes. Belongs to the peptidase C1 family. |
UniProt Protein Details: | Protein type:EC 3.4.22.16; Protease Chromosomal Location of Human Ortholog: 15q25.1 Cellular Component: cytosol; extracellular space; lysosome Molecular Function:aminopeptidase activity; caspase activator activity; cysteine-type endopeptidase activity; cysteine-type peptidase activity; endopeptidase activity; HLA-A specific activating MHC class I receptor activity; peptidase activity; protein binding; serine-type endopeptidase activity Biological Process: adaptive immune response; antigen processing and presentation; cellular protein metabolic process; immune response-regulating signal transduction; membrane protein proteolysis; metanephros development; negative regulation of apoptosis; positive regulation of angiogenesis; positive regulation of cell migration; positive regulation of cell proliferation; protein destabilization; proteolysis; proteolysis involved in cellular protein catabolic process; response to retinoic acid; surfactant homeostasis; T cell mediated cytotoxicity; zymogen activation |
NCBI Summary: | The protein encoded by this gene is a lysosomal cysteine proteinase important in the overall degradation of lysosomal proteins. It is composed of a dimer of disulfide-linked heavy and light chains, both produced from a single protein precursor. The encoded protein, which belongs to the peptidase C1 protein family, can act both as an aminopeptidase and as an endopeptidase. Increased expression of this gene has been correlated with malignant progression of prostate tumors. Alternate splicing of this gene results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jan 2016] |
UniProt Code: | P09668 |
NCBI GenInfo Identifier: | 288558851 |
NCBI Gene ID: | 1512 |
NCBI Accession: | P09668.4 |
UniProt Secondary Accession: | P09668,Q96NY6, Q9BUM7, B2RBK0, |
UniProt Related Accession: | P09668 |
Molecular Weight: | 37,394 Da |
NCBI Full Name: | Pro-cathepsin H |
NCBI Synonym Full Names: | cathepsin H |
NCBI Official Symbol: | CTSH |
NCBI Official Synonym Symbols: | ACC4; ACC5; CPSB; ACC-4; ACC-5 |
NCBI Protein Information: | pro-cathepsin H |
UniProt Protein Name: | Pro-cathepsin H |
Protein Family: | Pro-cathepsin |
UniProt Gene Name: | CTSH |
UniProt Entry Name: | CATH_HUMAN |