CTPS2 Antibody (PACO08665)
- SKU:
- PACO08665
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
抗体名: | CTPS2 Antibody (PACO08665) |
抗体コード: | PACO08665 |
サイズ: | 50ul |
宿主種: | Rabbit |
申し込み: | ELISA, WB |
推奨される希釈: | |
反応性: | Human, Mouse, Rat |
免疫原: | Human CTPS2 |
憲法: | Liquid |
ストレージバッファ: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles. |
精製方法: | Antigen Affinity Purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Non-conjugated |
シノニム: | CTP synthase II;CTPS2;DKFZp686C17207;FLJ43358;MGC32997 ; |
UniProt Protein Function: | CTPS2: Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Constitutes the rate-limiting enzyme in the synthesis of cytosine nucleotides. Belongs to the CTP synthase family. |
UniProt Protein Details: | Protein type:EC 6.3.4.2; Nucleotide Metabolism - pyrimidine; Ligase Chromosomal Location of Human Ortholog: Xp22 Cellular Component: cytosol Molecular Function:CTP synthase activity; protein binding Biological Process: nucleobase, nucleoside and nucleotide interconversion; pyrimidine nucleotide metabolic process |
NCBI Summary: | The protein encoded by this gene catalyzes the formation of CTP from UTP with the concomitant deamination of glutamine to glutamate. This protein is the rate-limiting enzyme in the synthesis of cytosine nucleotides, which play an important role in various metabolic processes and provide the precursors necessary for the synthesis of RNA and DNA. Cancer cells that exhibit increased cell proliferation also exhibit an increased activity of this encoded protein. Thus, this protein is an attractive target for selective chemotherapy. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013] |
UniProt Code: | Q9NRF8 |
NCBI GenInfo Identifier: | 74752919 |
NCBI Gene ID: | 56474 |
NCBI Accession: | Q9NRF8.1 |
UniProt Secondary Accession: | Q9NRF8,Q9BRI0, Q9H809, Q9H8K9, B3KWM2, |
UniProt Related Accession: | Q9NRF8 |
Molecular Weight: | 65,678 Da |
NCBI Full Name: | CTP synthase 2 |
NCBI Synonym Full Names: | CTP synthase 2 |
NCBI Official Symbol: | CTPS2 |
NCBI Protein Information: | CTP synthase 2 |
UniProt Protein Name: | CTP synthase 2 |
UniProt Synonym Protein Names: | CTP synthetase 2; UTP--ammonia ligase 2 |
Protein Family: | CTP synthase |
UniProt Gene Name: | CTPS2 |
UniProt Entry Name: | PYRG2_HUMAN |