CTGF Antibody (PACO32704)
- SKU:
- PACO32704
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- IHC
- Application:
- IF
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
抗体名: | CTGF Antibody (PACO32704) |
抗体コード: | PACO32704 |
サイズ: | 50ug |
宿主種: | Rabbit |
申し込み: | ELISA, IHC, IF |
推奨される希釈: | ELISA:1:2000-1:10000, IHC:1:20-1:200, IF:1:50-1:200 |
反応性: | Human |
免疫原: | Recombinant Human Connective tissue growth factor protein (253-349AA) |
憲法: | Liquid |
ストレージバッファ: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
精製方法: | >95%, Protein G purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Non-conjugated |
![]() | Immunofluorescent analysis of HepG2 cells using PACO32704 at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L). |
![]() | Immunohistochemistry of paraffin-embedded human lung cancer using PACO32704 at dilution of 1:100. |
バックグラウンド: | Major connective tissue mitoattractant secreted by vascular endothelial cells. Promotes proliferation and differentiation of chondrocytes. Mediates heparin- and divalent cation-dependent cell adhesion in many cell types including fibroblasts, myofibroblasts, endothelial and epithelial cells. Enhances fibroblast growth factor-induced DNA synthesis. |
シノニム: | Connective tissue growth factor (CCN family member 2) (Hypertrophic chondrocyte-specific protein 24) (Insulin-like growth factor-binding protein 8) (IBP-8) (IGF-binding protein 8) (IGFBP-8), CTGF, CCN2 HCS24 IGFBP8 |
UniProt Protein Function: | CTGF: Major connective tissue mitoattractant secreted by vascular endothelial cells. Promotes proliferation and differentiation of chondrocytes. Mediates heparin- and divalent cation-dependent cell adhesion in many cell types including fibroblasts, myofibroblasts, endothelial and epithelial cells. Enhances fibroblast growth factor-induced DNA synthesis. Belongs to the CCN family. 2 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:Cell adhesion; Secreted; Secreted, signal peptide Chromosomal Location of Human Ortholog: 6q23.2 Cellular Component: extracellular region; Golgi apparatus; intracellular membrane-bound organelle; plasma membrane Molecular Function:protein binding; protein C-terminus binding Biological Process: epidermis development; positive regulation of cell differentiation; positive regulation of JNK cascade; positive regulation of stress fiber formation; response to wounding; transcription initiation from RNA polymerase II promoter |
NCBI Summary: | The protein encoded by this gene is a mitogen that is secreted by vascular endothelial cells. The encoded protein plays a role in chondrocyte proliferation and differentiation, cell adhesion in many cell types, and is related to platelet-derived growth factor. Certain polymorphisms in this gene have been linked with a higher incidence of systemic sclerosis. [provided by RefSeq, Nov 2009] |
UniProt Code: | P29279 |
NCBI GenInfo Identifier: | 116241320 |
NCBI Gene ID: | 1490 |
NCBI Accession: | P29279.2 |
UniProt Secondary Accession: | P29279,Q6LCY0, Q96A79, Q96QX2, Q9UDL6, E1P578, |
UniProt Related Accession: | P29279 |
Molecular Weight: | 38kDa |
NCBI Full Name: | Connective tissue growth factor |
NCBI Synonym Full Names: | connective tissue growth factor |
NCBI Official Symbol: | CTGF |
NCBI Official Synonym Symbols: | CCN2; NOV2; HCS24; IGFBP8 |
NCBI Protein Information: | connective tissue growth factor |
UniProt Protein Name: | Connective tissue growth factor |
UniProt Synonym Protein Names: | CCN family member 2; Hypertrophic chondrocyte-specific protein 24; Insulin-like growth factor-binding protein 8; IBP-8; IGF-binding protein 8; IGFBP-8 |
Protein Family: | Connective tissue growth factor |
UniProt Gene Name: | CTGF |
Secondary Antibody |
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
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