CSH1 Antibody, FITC conjugated (PACO33014)
- SKU:
- PACO33014
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Antibody type:
- Polyclonal
- Conjugation:
- FITC
Frequently bought together:
Description
抗体名: | CSH1 Antibody, FITC conjugated (PACO33014) |
抗体コード: | PACO33014 |
サイズ: | 50ug |
宿主種: | Rabbit |
申し込み: | ELISA |
推奨される希釈: | |
反応性: | Human |
免疫原: | Recombinant Human Chorionic somatomammotropin hormone 1 protein (27-217AA) |
憲法: | Liquid |
ストレージバッファ: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
精製方法: | >95%, Protein G purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | FITC |
バックグラウンド: | Produced only during pregnancy and is involved in stimulating lactation, fetal growth and metabolism. Does not interact with GHR but only activates PRLR through zinc-induced dimerization. |
シノニム: | Chorionic somatomammotropin hormone 1 (Choriomammotropin) (Lactogen) (Placental lactogen) (PL), CSH1 |
UniProt Protein Function: | CSH1: Produced only during pregnancy and is involved in stimulating lactation, fetal growth and metabolism. Does not interact with GHR but only activates PRLR through zinc-induced dimerization. Belongs to the somatotropin/prolactin family. |
UniProt Protein Details: | Protein type:Secreted; Secreted, signal peptide Chromosomal Location of Human Ortholog: 17q24.2 Cellular Component: extracellular region Molecular Function:hormone activity; metal ion binding |
NCBI Summary: | The protein encoded by this gene is a member of the somatotropin/prolactin family of hormones and plays an important role in growth control. The gene is located at the growth hormone locus on chromosome 17 along with four other related genes in the same transcriptional orientation; an arrangement which is thought to have evolved by a series of gene duplications. Although the five genes share a remarkably high degree of sequence identity, they are expressed selectively in different tissues. Alternative splicing generates additional isoforms of each of the five growth hormones, leading to further diversity and potential for specialization. This particular family member is expressed mainly in the placenta and utilizes multiple transcription initiation sites. Expression of the identical mature proteins for chorionic somatomammotropin hormones 1 and 2 is upregulated during development, although the ratio of 1 to 2 increases by term. Mutations in this gene result in placental lactogen deficiency and Silver-Russell syndrome. [provided by RefSeq, Jul 2008] |
UniProt Code: | P0DML2 |
NCBI GenInfo Identifier: | 190034 |
NCBI Gene ID: | 1442 |
NCBI Accession: | AAA98621.1 |
UniProt Secondary Accession: | P0DML2,P01243, Q0VDB1, Q14407, |
UniProt Related Accession: | P0DML2 |
Molecular Weight: | 25,020 Da |
NCBI Full Name: | placental lactogen |
NCBI Synonym Full Names: | chorionic somatomammotropin hormone 1 (placental lactogen) |
NCBI Official Symbol: | CSH1 |
NCBI Official Synonym Symbols: | PL; CSA; CS-1; CSMT; hCS-1; hCS-A |
NCBI Protein Information: | chorionic somatomammotropin hormone 1; choriomammotropin; placental lactogen; chorionic somatomammotropin A; chorionic somatomammotropin-1 |
UniProt Protein Name: | Chorionic somatomammotropin hormone 1 |
UniProt Synonym Protein Names: | Lactogen; Placental lactogen; PL |
UniProt Gene Name: | CSH1 |
UniProt Entry Name: | CSH1_HUMAN |