CSF2RB Antibody (PACO54266)
- SKU:
- PACO54266
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- IHC
- Application:
- IF
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
抗体名: | CSF2RB Antibody (PACO54266) |
抗体コード: | PACO54266 |
サイズ: | 50ug |
宿主種: | Rabbit |
申し込み: | ELISA, IHC, IF |
推奨される希釈: | ELISA:1:2000-1:10000, IHC:1:20-1:200, IF:1:50-1:200 |
反応性: | Human |
免疫原: | Recombinant Human Cytokine receptor common subunit β protein (492-710AA) |
憲法: | Liquid |
ストレージバッファ: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
精製方法: | >95%, Protein G purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Non-conjugated |
![]() | Immunohistochemistry of paraffin-embedded human ovarian cancer using PACO54266 at dilution of 1:100. |
![]() | Immunofluorescence staining of Hela cells with PACO54266 at 1:66, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L). |
![]() | Immunohistochemistry of paraffin-embedded human cervical cancer using PACO54266 at dilution of 1:100. |
バックグラウンド: | High affinity receptor for interleukin-3, interleukin-5 and granulocyte-macrophage colony-stimulating factor. |
シノニム: | Cytokine receptor common subunit β (CDw131) (GM-CSF/IL-3/IL-5 receptor common β subunit) (CD antigen CD131), CSF2RB, IL3RB IL5RB |
UniProt Protein Function: | CSF2RB: a common beta chain of the high affinity receptor for IL-3, IL-5 and CSF. A type I cytokine family of receptor. Defects are a cause of congenital pulmonary alveolar proteinosis (PAP) [MIM:265120]. PAP is an autosomal recessive fatal respiratory disease. |
UniProt Protein Details: | Protein type:Membrane protein, integral; Receptor, cytokine Chromosomal Location of Human Ortholog: 22q13.1 Cellular Component: granulocyte macrophage colony-stimulating factor receptor complex; plasma membrane Molecular Function:interleukin-3 receptor activity; interleukin-5 receptor activity; protein binding; protein-tyrosine kinase activity; Ras guanyl-nucleotide exchange factor activity; receptor activity Biological Process: cellular protein metabolic process; MAPKKK cascade; respiratory gaseous exchange Disease: Surfactant Metabolism Dysfunction, Pulmonary, 5 |
NCBI Summary: | The protein encoded by this gene is the common beta chain of the high affinity receptor for IL-3, IL-5 and CSF. Defects in this gene have been reported to be associated with protein alveolar proteinosis (PAP). [provided by RefSeq, Jul 2008] |
UniProt Code: | P32927 |
NCBI GenInfo Identifier: | 1345923 |
NCBI Gene ID: | 1439 |
NCBI Accession: | P32927.2 |
UniProt Secondary Accession: | P32927,Q5JZI1, Q6ICE0, |
UniProt Related Accession: | P32927 |
Molecular Weight: | 97,976 Da |
NCBI Full Name: | Cytokine receptor common subunit beta |
NCBI Synonym Full Names: | colony stimulating factor 2 receptor beta common subunit |
NCBI Official Symbol: | CSF2RB |
NCBI Official Synonym Symbols: | CD131; IL3RB; IL5RB; SMDP5; CDw131 |
NCBI Protein Information: | cytokine receptor common subunit beta |
UniProt Protein Name: | Cytokine receptor common subunit beta |
UniProt Synonym Protein Names: | CDw131; GM-CSF/IL-3/IL-5 receptor common beta subunit; CD_antigen: CD131 |
Protein Family: | Cytokine receptor |
UniProt Gene Name: | CSF2RB |
UniProt Entry Name: | IL3RB_HUMAN |
Secondary Antibody |
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
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