CRYBA4 Antibody, FITC conjugated (PACO25959)
- SKU:
- PACO25959
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Antibody type:
- Polyclonal
- Conjugation:
- FITC
Frequently bought together:
Description
抗体名: | CRYBA4 Antibody, FITC conjugated (PACO25959) |
抗体コード: | PACO25959 |
サイズ: | 50ug |
宿主種: | Rabbit |
申し込み: | ELISA |
推奨される希釈: | |
反応性: | Human |
免疫原: | Recombinant Human Beta-crystallin A4 protein (2-196AA) |
憲法: | Liquid |
ストレージバッファ: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
精製方法: | >95%, Protein G purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | FITC |
バックグラウンド: | Crystallins are the dominant structural components of the vertebrate eye lens. |
シノニム: | Beta-crystallin A4 (Beta-A4 crystallin), CRYBA4 |
UniProt Protein Function: | CRYBA4: a major structural protein of the eye lens. A member of the beta/gamma-crystallin family. |
UniProt Protein Details: | Chromosomal Location of Human Ortholog: 22q12.1 Molecular Function:protein binding Biological Process: camera-type eye development; visual perception Disease: Cataract 23 |
NCBI Summary: | Crystallins are separated into two classes: taxon-specific, or enzyme, and ubiquitous. The latter class constitutes the major proteins of vertebrate eye lens and maintains the transparency and refractive index of the lens. Since lens central fiber cells lose their nuclei during development, these crystallins are made and then retained throughout life, making them extremely stable proteins. Mammalian lens crystallins are divided into alpha, beta, and gamma families; beta and gamma crystallins are also considered as a superfamily. Alpha and beta families are further divided into acidic and basic groups. Seven protein regions exist in crystallins: four homologous motifs, a connecting peptide, and N- and C-terminal extensions. Beta-crystallins, the most heterogeneous, differ by the presence of the C-terminal extension (present in the basic group, none in the acidic group). Beta-crystallins form aggregates of different sizes and are able to self-associate to form dimers or to form heterodimers with other beta-crystallins. This gene, a beta acidic group member, is part of a gene cluster with beta-B1, beta-B2, and beta-B3. [provided by RefSeq, Jul 2008] |
UniProt Code: | P53673 |
NCBI GenInfo Identifier: | 2506318 |
NCBI Gene ID: | 1413 |
NCBI Accession: | P53673.3 |
UniProt Secondary Accession: | P53673,Q4VB22, Q6ICE4, |
UniProt Related Accession: | P53673 |
Molecular Weight: | 22,374 Da |
NCBI Full Name: | Beta-crystallin A4 |
NCBI Synonym Full Names: | crystallin beta A4 |
NCBI Official Symbol: | CRYBA4 |
NCBI Official Synonym Symbols: | CYRBA4; CTRCT23; MCOPCT4 |
NCBI Protein Information: | beta-crystallin A4 |
UniProt Protein Name: | Beta-crystallin A4 |
UniProt Synonym Protein Names: | Beta-A4 crystallin |
Protein Family: | Beta-crystallin |
UniProt Gene Name: | CRYBA4 |
UniProt Entry Name: | CRBA4_HUMAN |