UniProt Protein Function: | CREB3L4: Transcriptional activator that may play a role in the unfolded protein response. Binds to the UPR element (UPRE) but not to CRE element. Preferentially binds DNA with to the consensus sequence 5'-T[GT]ACGT[GA][GT]-3' and has transcriptional activation activity from UPRE. Binds to NF-kappa-B site and has transcriptional activation activity from NF-kappa-B-containing regulatory elements. Belongs to the bZIP family. ATF subfamily.Protein type: Transcription factor; Endoplasmic reticulum; Membrane protein, integralChromosomal Location of Human Ortholog: 1q21.3Cellular Component: endoplasmic reticulum; Golgi apparatusBiological Process: positive regulation of transcription from RNA polymerase II promoter |
UniProt Protein Details: | |
NCBI Summary: | This gene encodes a CREB (cAMP responsive element binding) protein with a transmembrane domain which localizes it to the ER membrane. The encoded protein is a transcriptional activator which contains a dimerization domain, and this protein may function in a number of processing pathways including protein processing. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2011] |
UniProt Code: | Q8TEY5 |
NCBI GenInfo Identifier: | 74751463 |
NCBI Gene ID: | 148327 |
NCBI Accession: | Q8TEY5.1 |
UniProt Secondary Accession: | Q8TEY5,Q5T4L0, Q86YW6, D3DV62 |
UniProt Related Accession: | Q8TEY5 |
Molecular Weight: | 41,275 Da |
NCBI Full Name: | Cyclic AMP-responsive element-binding protein 3-like protein 4 |
NCBI Synonym Full Names: | cAMP responsive element binding protein 3 like 4 |
NCBI Official Symbol: | CREB3L4 |
NCBI Official Synonym Symbols: | JAL; hJAL; ATCE1; CREB3; CREB4; AIBZIP |
NCBI Protein Information: | cyclic AMP-responsive element-binding protein 3-like protein 4 |
UniProt Protein Name: | Cyclic AMP-responsive element-binding protein 3-like protein 4 |
UniProt Synonym Protein Names: | Androgen-induced basic leucine zipper protein; AIbZIP |
Protein Family: | Cyclic AMP-responsive element-binding protein 3-like protein |
UniProt Gene Name: | CREB3L4 |
UniProt Entry Name: | CR3L4_HUMAN |