CPLX1 Antibody (PACO08565)
- SKU:
- PACO08565
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
抗体名: | CPLX1 Antibody (PACO08565) |
抗体コード: | PACO08565 |
サイズ: | 50ul |
宿主種: | Rabbit |
申し込み: | ELISA, WB |
推奨される希釈: | |
反応性: | Human, Mouse, Rat |
免疫原: | Human CPLX1 |
憲法: | Liquid |
ストレージバッファ: | PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles. |
精製方法: | Antigen Affinity Purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Non-conjugated |
シノニム: | complexin 1;CPLX1;CPX-I;CPX1 ;complexin1 |
UniProt Protein Function: | CPLX1: Positively regulates a late step in synaptic vesicle exocytosis. Organizes the SNAREs into a cross-linked zigzag topology that, when interposed between the vesicle and plasma membranes, is incompatible with fusion, thereby preventing SNAREs from releasing neurotransmitters until an action potential arrives at the synapse. Also involved in glucose-induced secretion of insulin by pancreatic beta-cells. Belongs to the complexin/synaphin family. |
UniProt Protein Details: | Protein type:Vesicle Chromosomal Location of Human Ortholog: 4p16.3 Cellular Component: cytosol Biological Process: exocytosis; glutamate secretion; neurotransmitter secretion; regulation of exocytosis; synaptic transmission Disease: Wolf-hirschhorn Syndrome |
NCBI Summary: | Proteins encoded by the complexin/synaphin gene family are cytosolic proteins that function in synaptic vesicle exocytosis. These proteins bind syntaxin, part of the SNAP receptor. The protein product of this gene binds to the SNAP receptor complex and disrupts it, allowing transmitter release. [provided by RefSeq, Jul 2008] |
UniProt Code: | O14810 |
NCBI GenInfo Identifier: | 5921800 |
NCBI Gene ID: | 10815 |
NCBI Accession: | O14810.1 |
UniProt Secondary Accession: | O14810,A6NI80, B2R4R5, D3DVN3, F1T0G1, |
UniProt Related Accession: | O14810 |
Molecular Weight: | 15kDa |
NCBI Full Name: | Complexin-1 |
NCBI Synonym Full Names: | complexin 1 |
NCBI Official Symbol: | CPLX1 |
NCBI Official Synonym Symbols: | CPX1; CPX-I |
NCBI Protein Information: | complexin-1 |
UniProt Protein Name: | Complexin-1 |
UniProt Synonym Protein Names: | Complexin I; CPX I; Synaphin-2 |
UniProt Gene Name: | CPLX1 |