CNTFR Antibody (PACO25841)
- SKU:
- PACO25841
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Application:
- IHC
- Application:
- IF
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
抗体名: | CNTFR Antibody (PACO25841) |
抗体コード: | PACO25841 |
サイズ: | 50ug |
宿主種: | Rabbit |
申し込み: | ELISA, WB, IHC, IF |
推奨される希釈: | ELISA:1:2000-1:10000, WB:1:500-1:5000, IHC:1:20-1:200, IF:1:50-1:200 |
反応性: | Human |
免疫原: | Recombinant Human Ciliary neurotrophic factor receptor subunit α protein (106-342AA) |
憲法: | Liquid |
ストレージバッファ: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
精製方法: | >95%, Protein G purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Non-conjugated |
![]() | Western blot All lanes: CNTFR antibody at 2µg/ml + Hela whole cell lysate Secondary Goat polyclonal to rabbit IgG at 1/10000 dilution Predicted band size: 41 kDa Observed band size: 41 kDa . |
![]() | Immunohistochemistry of paraffin-embedded human skeletal muscle tissue using PACO25841 at dilution of 1:100. |
![]() | Immunohistochemistry of paraffin-embedded human colon cancer using PACO25841 at dilution of 1:100. |
バックグラウンド: | Binds to CNTF. The α subunit provides the receptor specificity. |
シノニム: | Ciliary neurotrophic factor receptor subunit α (CNTF receptor subunit alpha) (CNTFR-alpha), CNTFR |
UniProt Protein Function: | CNTFR: Binds to CNTF. The alpha subunit provides the receptor specificity. Belongs to the type I cytokine receptor family. Type 3 subfamily. |
UniProt Protein Details: | Protein type:Membrane protein, GPI anchor; Receptor, misc. Chromosomal Location of Human Ortholog: 9p13 Cellular Component: extrinsic to membrane Molecular Function:cytokine binding; ciliary neurotrophic factor receptor activity; receptor binding Biological Process: nervous system development; suckling behavior; positive regulation of cell proliferation; negative regulation of neuron apoptosis; signal transduction; sex differentiation |
NCBI Summary: | This gene encodes a member of the type 1 cytokine receptor family. The encoded protein is the ligand-specific component of a tripartite receptor for ciliary neurotrophic factor, which plays a critical role in neuronal cell survival, differentiation and gene expression. Binding of ciliary neurotrophic factor to the encoded protein recruits the transmembrane components of the receptor, gp130 and leukemia inhibitory factor receptor, facilitating signal transduction. Single nucleotide polymorphisms in this gene may be associated with variations in muscle strength, as well as early onset of eating disorders. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, May 2011] |
UniProt Code: | P26992 |
NCBI GenInfo Identifier: | 1352099 |
NCBI Gene ID: | 1271 |
NCBI Accession: | P26992.2 |
UniProt Related Accession: | P26992 |
Molecular Weight: | 40kDa |
NCBI Full Name: | Ciliary neurotrophic factor receptor subunit alpha |
NCBI Synonym Full Names: | ciliary neurotrophic factor receptor |
NCBI Official Symbol: | CNTFR |
NCBI Protein Information: | ciliary neurotrophic factor receptor subunit alpha |
UniProt Protein Name: | Ciliary neurotrophic factor receptor subunit alpha |
Protein Family: | Ciliary neurotrophic factor receptor |
UniProt Gene Name: | CNTFR |
UniProt Entry Name: | CNTFR_HUMAN |