CNNM2 Antibody (PACO59409)
- SKU:
- PACO59409
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- IHC
- Application:
- IF
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
抗体名: | CNNM2 Antibody (PACO59409) |
抗体コード: | PACO59409 |
サイズ: | 50ug |
宿主種: | Rabbit |
申し込み: | ELISA, IHC, IF |
推奨される希釈: | ELISA:1:2000-1:10000, IHC:1:200-1:500, IF:1:50-1:200 |
反応性: | Human |
免疫原: | Recombinant Human Metal transporter CNNM2 protein (739-875AA) |
憲法: | Liquid |
ストレージバッファ: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
精製方法: | >95%, Protein G purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Non-conjugated |
![]() | IHC image of PACO59409 diluted at 1:300 and staining in paraffin-embedded human kidney tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system. |
![]() | Immunofluorescence staining of HepG2 cells with PACO59409 at 1:100, counter-stained with DAPI. The cells were fixed in 4% formaldehyde, permeabilized using 0.2% Triton X-100 and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L). |
バックグラウンド: | Divalent metal cation transporter. Mediates transport of divalent metal cations in an order of Mg(2+) > Co(2+) > Mn(2+) > Sr(2+) > Ba(2+) > Cu(2+) > Fe(2+) (By similarity). |
シノニム: | Metal transporter CNNM2 (Ancient conserved domain-containing protein 2) (Cyclin-M2), CNNM2, ACDP2 |
UniProt Protein Function: | Divalent metal cation transporter. Mediates transport of divalent metal cations in an order of Mg2+ > Co2+ > Mn2+ > Sr2+ > Ba2+ > Cu2+ > Fe2+. |
NCBI Summary: | This gene encodes a member of the ancient conserved domain containing protein family. Members of this protein family contain a cyclin box motif and have structural similarity to the cyclins. The encoded protein may play an important role in magnesium homeostasis by mediating the epithelial transport and renal reabsorption of Mg2+. Mutations in this gene are associated with renal hypomagnesemia. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2011] |
UniProt Code: | Q9H8M5 |
NCBI GenInfo Identifier: | 156631023 |
NCBI Gene ID: | 54805 |
NCBI Accession: | Q9H8M5.2 |
UniProt Secondary Accession: | Q9H8M5,Q5T569, Q5T570, Q8WU59, Q9H952, Q9NRK5, Q9NXT4 |
UniProt Related Accession: | Q9H8M5 |
Molecular Weight: | 60,487 Da |
NCBI Full Name: | Metal transporter CNNM2 |
NCBI Synonym Full Names: | cyclin and CBS domain divalent metal cation transport mediator 2 |
NCBI Official Symbol: | CNNM2 |
NCBI Official Synonym Symbols: | ACDP2; HOMG6; HOMGSMR |
NCBI Protein Information: | metal transporter CNNM2 |
UniProt Protein Name: | Metal transporter CNNM2 |
UniProt Synonym Protein Names: | Ancient conserved domain-containing protein 2; Cyclin-M2 |
Protein Family: | Metal transporter |
UniProt Gene Name: | CNNM2 |
UniProt Entry Name: | CNNM2_HUMAN |