CNKSR2 Antibody, HRP conjugated (PACO25834)
- SKU:
- PACO25834
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Antibody type:
- Polyclonal
- Conjugation:
- HRP
Frequently bought together:
Description
抗体名: | CNKSR2 Antibody, HRP conjugated (PACO25834) |
抗体コード: | PACO25834 |
サイズ: | 50ug |
宿主種: | Rabbit |
申し込み: | ELISA |
推奨される希釈: | |
反応性: | Human |
免疫原: | Recombinant Human Connector enhancer of kinase suppressor of ras 2 protein (650-800AA) |
憲法: | Liquid |
ストレージバッファ: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
精製方法: | >95%, Protein G purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | HRP |
バックグラウンド: | May function as an adapter protein or regulator of Ras signaling pathways. |
シノニム: | Connector enhancer of kinase suppressor of ras 2 (Connector enhancer of KSR 2) (CNK homolog protein 2) (CNK2), CNKSR2, CNK2 KIAA0902 KSR2 |
UniProt Protein Function: | CNKSR2: a RAF-binding multidomain protein required for RAS signaling. Contains several protein-protein interaction domains. Its PH domain interacts with Rho in a GTP-dependent manner. Associates with Rhophilin and RalGDS, Rho and Ras effector molecules. Two alternatively spliced isoforms have been described. |
UniProt Protein Details: | Protein type:Adaptor/scaffold Chromosomal Location of Human Ortholog: Xp22.12 Cellular Component: Golgi apparatus; postsynaptic membrane; neuron projection; cell soma; plasma membrane Molecular Function:identical protein binding Biological Process: regulation of signal transduction |
NCBI Summary: | This gene encodes a multidomain protein that functions as a scaffold protein to mediate the mitogen-activated protein kinase pathways downstream from Ras. This gene product is induced by vitamin D and inhibits apoptosis in certain cancer cells. It may also play a role in ternary complex assembly of synaptic proteins at the postsynaptic membrane and coupling of signal transduction to membrane/cytoskeletal remodeling. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2009] |
UniProt Code: | Q8WXI2 |
NCBI GenInfo Identifier: | 281306725 |
NCBI Gene ID: | 22866 |
NCBI Accession: | NP_001162118.1 |
UniProt Related Accession: | Q8WXI2 |
Molecular Weight: | |
NCBI Full Name: | connector enhancer of kinase suppressor of ras 2 isoform 2 |
NCBI Synonym Full Names: | connector enhancer of kinase suppressor of Ras 2 |
NCBI Official Symbol: | CNKSR2 |
NCBI Official Synonym Symbols: | CNK2; KSR2; MAGUIN; MRXSHG |
NCBI Protein Information: | connector enhancer of kinase suppressor of ras 2 |
UniProt Protein Name: | Connector enhancer of kinase suppressor of ras 2 |
UniProt Synonym Protein Names: | CNK homolog protein 2 |
UniProt Gene Name: | CNKSR2 |
UniProt Entry Name: | CNKR2_HUMAN |