CLPTM1L Antibody (PACO19487)
- SKU:
- PACO19487
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
抗体名: | CLPTM1L Antibody (PACO19487) |
抗体コード: | PACO19487 |
サイズ: | 50ul |
宿主種: | Rabbit |
申し込み: | ELISA, IHC |
推奨される希釈: | ELISA:1:1000-1:5000, IHC:1:50-1:200 |
反応性: | Human |
免疫原: | Synthetic peptide of human CLPTM1L |
憲法: | Liquid |
ストレージバッファ: | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
精製方法: | Antigen affinity purification |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Non-conjugated |
![]() | The image on the left is immunohistochemistry of paraffin-embedded Human esophagus cancer tissue using PACO19487(CLPTM1L Antibody) at dilution 1/60, on the right is treated with synthetic peptide. (Original magnification: x200). |
![]() | The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using PACO19487(CLPTM1L Antibody) at dilution 1/60, on the right is treated with synthetic peptide. (Original magnification: x200). |
バックグラウンド: | Cleft lip and palate transmembrane protein 1-like protein (CLPTM1-like protein), also known as cisplatin resistance-related protein 9 (CRR9p), is a protein that in humans is encoded by the CLPTM1L gene. CRR9p is associated with cisplatin-induced apoptosis. CLPTM1L, which lies within a cancer susceptibility locus on chromosome 5 (5p15.33), has been found to be commonly over-expressed in lung tumors and to confer resistance to apoptosis caused by genotoxic agents in association with up-regulation of the anti-apoptotic protein, Bcl-xL. |
シノニム: | CLPTM1-like |
UniProt Protein Function: | CLPTM1L: Enhances cisplatin-mediated apoptosis, when overexpressed. Belongs to the CLPTM1 family. 2 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:Membrane protein, integral; Membrane protein, multi-pass Chromosomal Location of Human Ortholog: 5p15.33 Cellular Component: membrane |
NCBI Summary: | The protein encoded by this gene is a membrane protein whose overexpression in cisplatin-sensitive cells causes apoptosis. Polymorphisms in this gene have been reported to increase susceptibility to several cancers, including lung, pancreatic, and breast cancers. [provided by RefSeq, Nov 2015] |
UniProt Code: | Q96KA5 |
NCBI GenInfo Identifier: | 74732209 |
NCBI Gene ID: | 81037 |
NCBI Accession: | Q96KA5.1 |
UniProt Secondary Accession: | Q96KA5,Q658W6, Q7LG29, Q96AZ0, Q9H3N4, D3DTC1, |
UniProt Related Accession: | Q96KA5 |
Molecular Weight: | 58,356 Da |
NCBI Full Name: | Cleft lip and palate transmembrane protein 1-like protein |
NCBI Synonym Full Names: | CLPTM1 like |
NCBI Official Symbol: | CLPTM1L |
NCBI Official Synonym Symbols: | CRR9 |
NCBI Protein Information: | cleft lip and palate transmembrane protein 1-like protein |
UniProt Protein Name: | Cleft lip and palate transmembrane protein 1-like protein |
UniProt Synonym Protein Names: | Cisplatin resistance-related protein 9; CRR9p |
Protein Family: | Cleft lip and palate transmembrane protein 1-like protein |
UniProt Gene Name: | CLPTM1L |
UniProt Entry Name: | CLP1L_HUMAN |
Antibodies |
Anti-CLPTM1L Antibody (CAB10468) |
Secondary Antibody |
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014) |
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