CLINT1 Antibody (PACO51434)
- SKU:
- PACO51434
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Application:
- IHC
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
抗体名: | CLINT1 Antibody (PACO51434) |
抗体コード: | PACO51434 |
サイズ: | 50ug |
宿主種: | Rabbit |
申し込み: | ELISA, WB, IHC |
推奨される希釈: | ELISA:1:2000-1:10000, WB:1:200-1:3000, IHC:1:20-1:200 |
反応性: | Human, Mouse, Rat |
免疫原: | Recombinant Human Clathrin interactor 1 protein (1-625AA) |
憲法: | Liquid |
ストレージバッファ: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
精製方法: | >95%, Protein G purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Non-conjugated |
Immunohistochemistry of paraffin-embedded human prostate cancer using PACO51434 at dilution of 1:100. | |
Western Blot. Positive WB detected in: Hela whole cell lysate, HepG2 whole cell lysate, Rat liver tissue, Mouse liver tissue. All lanes: CLINT1 antibody at 2µg/ml. Secondary. Goat polyclonal to rabbit IgG at 1/50000 dilution. Predicted band size: 69, 71 kDa. Observed band size: 69 kDa. | |
Immunohistochemistry of paraffin-embedded human brain tissue using PACO51434 at dilution of 1:100. |
バックグラウンド: | Binds to membranes enriched in phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2). May have a role in transport via clathrin-coated vesicles from the trans-Golgi network to endosomes. Stimulates clathrin assembly. |
シノニム: | Clathrin interactor 1 (Clathrin-interacting protein localized in the trans-Golgi region) (Clint) (Enthoprotin) (Epsin-4) (Epsin-related protein) (EpsinR), CLINT1, ENTH EPN4 EPNR KIAA0171 |
UniProt Protein Function: | ENTH: Binds to membranes enriched in phosphatidylinositol 4,5- bisphosphate (PtdIns(4,5)P2). May have a role in transport via clathrin-coated vesicles from the trans-Golgi network to endosomes. Stimulates clathrin assembly. Belongs to the epsin family. 3 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:Motility/polarity/chemotaxis; Adaptor/scaffold Chromosomal Location of Human Ortholog: 5q33.3 Cellular Component: nucleoplasm; Golgi apparatus; intracellular membrane-bound organelle; membrane; clathrin-coated vesicle; perinuclear region of cytoplasm; cytosol Molecular Function:protein binding; clathrin binding; lipid binding Biological Process: clathrin cage assembly; endocytosis; post-Golgi vesicle-mediated transport Disease: Schizophrenia 1 |
NCBI Summary: | This gene encodes a protein with similarity to the epsin family of endocytic adapter proteins. The encoded protein interacts with clathrin, the adapter protein AP-1 and phosphoinositides. This protein may be involved in the formation of clathrin coated vesicles and trafficking between the trans-Golgi network and endosomes. Mutations in this gene are associated with a susceptibility to schizophrenia and psychotic disorders. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2010] |
UniProt Code: | Q14677 |
NCBI GenInfo Identifier: | 41016993 |
NCBI Gene ID: | 9685 |
NCBI Accession: | Q14677.1 |
UniProt Related Accession: | Q14677 |
Molecular Weight: | |
NCBI Full Name: | Clathrin interactor 1 |
NCBI Synonym Full Names: | clathrin interactor 1 |
NCBI Official Symbol: | CLINT1 |
NCBI Official Synonym Symbols: | ENTH; EPN4; EPNR; CLINT |
NCBI Protein Information: | clathrin interactor 1 |
UniProt Protein Name: | Clathrin interactor 1 |
UniProt Synonym Protein Names: | Clathrin-interacting protein localized in the trans-Golgi region; Clint; Enthoprotin; Epsin-4; Epsin-related protein; EpsinR |
Protein Family: | Enterotoxin |
UniProt Gene Name: | CLINT1 |
UniProt Entry Name: | EPN4_HUMAN |