CLEC10A Antibody, Biotin conjugated (PACO63814)
- SKU:
- PACO63814
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Antibody type:
- Polyclonal
- Conjugation:
- Biotin
Frequently bought together:
Description
抗体名: | CLEC10A Antibody, Biotin conjugated (PACO63814) |
抗体コード: | PACO63814 |
サイズ: | 50ul |
宿主種: | Rabbit |
申し込み: | ELISA |
推奨される希釈: | |
反応性: | Human |
免疫原: | Recombinant Human C-type lectin domain family 10 member A protein (66-316AA) |
憲法: | Liquid |
ストレージバッファ: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
精製方法: | Antigen Affinity Purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Biotin |
バックグラウンド: | Probable role in regulating adaptive and innate immune responses. Binds in a calcium-dependent manner to terminal galactose and N-acetylgalactosamine units, linked to serine or threonine. These sugar moieties are known as Tn-Ag and are expressed in a variety of carcinoma cells. |
シノニム: | C-type lectin domain family 10 member A (C-type lectin superfamily member 14) (Macrophage lectin 2) (CD antigen CD301), CLEC10A, CLECSF13 CLECSF14 HML |
UniProt Protein Function: | CLEC10A: Probable role in regulating adaptive and innate immune responses. Binds in a calcium-dependent manner to terminal galactose and N-acetylgalactosamine units, linked to serine or threonine. These sugar moieties are known as Tn-Ag and are expressed in a variety of carcinoma cells. 3 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:Membrane protein, integral Chromosomal Location of Human Ortholog: 17p13.1 Cellular Component: integral to membrane; plasma membrane Molecular Function:carbohydrate binding Biological Process: innate immune response; endocytosis |
NCBI Summary: | This gene encodes a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. Members of this family share a common protein fold and have diverse functions, such as cell adhesion, cell-cell signalling, glycoprotein turnover, and roles in inflammation and immune response. The encoded type 2 transmembrane protein may function as a cell surface antigen. Two transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jul 2008] |
UniProt Code: | Q8IUN9 |
NCBI GenInfo Identifier: | 59797948 |
NCBI Gene ID: | 10462 |
NCBI Accession: | Q8IUN9.1 |
UniProt Related Accession: | Q8IUN9 |
Molecular Weight: | |
NCBI Full Name: | C-type lectin domain family 10 member A |
NCBI Synonym Full Names: | C-type lectin domain containing 10A |
NCBI Official Symbol: | CLEC10A |
NCBI Official Synonym Symbols: | HML; MGL; HML2; CD301; CLECSF13; CLECSF14 |
NCBI Protein Information: | C-type lectin domain family 10 member A |
UniProt Protein Name: | C-type lectin domain family 10 member A |
UniProt Synonym Protein Names: | C-type lectin superfamily member 14; Macrophage lectin 2; CD_antigen: CD301 |
UniProt Gene Name: | CLEC10A |
UniProt Entry Name: | CLC10_HUMAN |