CIAPIN1 Antibody, HRP conjugated (PACO36675)
- SKU:
- PACO36675
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Antibody type:
- Polyclonal
- Conjugation:
- HRP
Frequently bought together:
Description
抗体名: | CIAPIN1 Antibody, HRP conjugated (PACO36675) |
抗体コード: | PACO36675 |
サイズ: | 50ug |
宿主種: | Rabbit |
申し込み: | ELISA |
推奨される希釈: | |
反応性: | Human |
免疫原: | Recombinant Human Anamorsin protein (1-312AA) |
憲法: | Liquid |
ストレージバッファ: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
精製方法: | >95%, Protein G purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | HRP |
バックグラウンド: | Has anti-apoptotic effects in the cell. Involved in negative control of cell death upon cytokine withdrawal. Promotes development of hematopoietic cells (By similarity). Component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery. Required for the maturation of extramitochondrial Fe-S proteins. Part of an electron transfer chain functioning in an early step of cytosolic Fe-S biogenesis. Electrons are transferred to the Fe-S cluster from NADPH via the FAD- and FMN-containing protein NDOR1. |
シノニム: | Anamorsin (Cytokine-induced apoptosis inhibitor 1) (Fe-S cluster assembly protein DRE2 homolog), CIAPIN1 |
UniProt Protein Function: | CIAPIN1: May be required for the maturation of extramitochondrial Fe/S proteins. Has anti-apoptotic effects in the cell. Involved in negative control of cell death upon cytokine withdrawal. Promotes development of hematopoietic cells. Belongs to the anamorsin family. 3 isoforms of the human protein are produced by alternative splicing. |
UniProt Protein Details: | Protein type:Apoptosis Chromosomal Location of Human Ortholog: 16q21 Cellular Component: cytoplasm; nucleolus; nucleoplasm Molecular Function:protein binding Biological Process: iron-sulfur cluster assembly; negative regulation of apoptosis |
NCBI Summary: | CIAPIN1 is a cytokine-induced inhibitor of apoptosis with no relation to apoptosis regulatory molecules of the BCL2 (MIM 151430) or CASP (see MIM 147678) families. Expression of CIAPIN1 is dependent on growth factor stimulation (Shibayama et al., 2004 [PubMed 14970183]).[supplied by OMIM, Mar 2008] |
UniProt Code: | Q6FI81 |
NCBI GenInfo Identifier: | 57012667 |
NCBI Gene ID: | 57019 |
NCBI Accession: | Q6FI81.2 |
UniProt Secondary Accession: | Q6FI81,O75206, O75207, Q9H0W1, Q9P1L7, A8K8B6, |
UniProt Related Accession: | Q6FI81 |
Molecular Weight: | 32,213 Da |
NCBI Full Name: | Anamorsin |
NCBI Synonym Full Names: | cytokine induced apoptosis inhibitor 1 |
NCBI Official Symbol: | CIAPIN1 |
NCBI Official Synonym Symbols: | DRE2; PRO0915; Anamorsin |
NCBI Protein Information: | anamorsin |
UniProt Protein Name: | Anamorsin |
UniProt Synonym Protein Names: | Cytokine-induced apoptosis inhibitor 1 |
Protein Family: | Anamorsin |
UniProt Gene Name: | CIAPIN1 |
UniProt Entry Name: | CPIN1_HUMAN |