CHST1 Antibody (PACO05568)
- SKU:
- PACO05568
- Product type:
- Antibody
- Reactivity:
- Human
- Reactivity:
- Mouse
- Reactivity:
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
抗体名: | CHST1 Antibody (PACO05568) |
抗体コード: | PACO05568 |
サイズ: | 50ug |
宿主種: | Rabbit |
申し込み: | ELISA, WB |
推奨される希釈: | ELISA:1:10000, WB:1:500-1:2000 |
反応性: | Human, Mouse, Rat |
免疫原: | Synthesized peptide derived from the Internal region of human CHST1. |
憲法: | Liquid |
ストレージバッファ: | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
精製方法: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Non-conjugated |
シノニム: | CHST1; Carbohydrate sulfotransferase 1; Galactose/N-acetylglucosamine/N-acetylglucosamine 6-O-sulfotransferase 1; GST-1; Keratan sulfate Gal-6 sulfotransferase; KS6ST; KSGal6ST; KSST |
UniProt Protein Function: | CHST1: Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the transfer of sulfate to position 6 of galactose (Gal) residues of keratan. Has a preference for sulfating keratan sulfate, but it also transfers sulfate to the unsulfated polymer. The sulfotransferase activity on sialyl LacNAc structures is much higher than the corresponding desialylated substrate, and only internal Gal residues are sulfated. May function in the sulfation of sialyl N- acetyllactosamine oligosaccharide chains attached to glycoproteins. Participates in biosynthesis of selectin ligands. Selectin ligands are present in high endothelial cells (HEVs) and play a central role in lymphocyte homing at sites of inflammation. Belongs to the sulfotransferase 1 family. Gal/GlcNAc/GalNAc subfamily. |
UniProt Protein Details: | Protein type:EC 2.8.2.21; Membrane protein, integral; Glycan Metabolism - keratan sulfate biosynthesis; Transferase Chromosomal Location of Human Ortholog: 11p11.2 Cellular Component: Golgi membrane Molecular Function:keratan sulfotransferase activity; N-acetylglucosamine 6-O-sulfotransferase activity; sulfotransferase activity Biological Process: galactose metabolic process; keratan sulfate biosynthetic process; keratan sulfate metabolic process; polysaccharide metabolic process; sulfur metabolic process |
NCBI Summary: | This locus encodes a member of the keratin sulfotransferase family of proteins. The encoded enzyme catalyzes the sulfation of the proteoglycan keratin. [provided by RefSeq, Aug 2011] |
UniProt Code: | O43916 |
NCBI GenInfo Identifier: | 61211700 |
NCBI Gene ID: | 8534 |
NCBI Accession: | O43916.1 |
UniProt Secondary Accession: | O43916,D3DQP2, |
UniProt Related Accession: | O43916 |
Molecular Weight: | 46,715 Da |
NCBI Full Name: | Carbohydrate sulfotransferase 1 |
NCBI Synonym Full Names: | carbohydrate sulfotransferase 1 |
NCBI Official Symbol: | CHST1 |
NCBI Official Synonym Symbols: | C6ST; KSST; GST-1; KS6ST; KSGal6ST |
NCBI Protein Information: | carbohydrate sulfotransferase 1 |
UniProt Protein Name: | Carbohydrate sulfotransferase 1 |
UniProt Synonym Protein Names: | Galactose/N-acetylglucosamine/N-acetylglucosamine 6-O-sulfotransferase 1; GST-1; Keratan sulfate Gal-6 sulfotransferase; KS6ST; KSGal6ST; KSST |
Protein Family: | Carbohydrate sulfotransferase |
UniProt Gene Name: | CHST1 |
UniProt Entry Name: | CHST1_HUMAN |