CHRFAM7A Antibody (PACO08419)
- SKU:
- PACO08419
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Application:
- WB
- Antibody type:
- Polyclonal
- Conjugation:
- Unconjugated
Frequently bought together:
Description
抗体名: | CHRFAM7A Antibody (PACO08419) |
抗体コード: | PACO08419 |
サイズ: | 50ul |
宿主種: | Rabbit |
申し込み: | ELISA, WB |
推奨される希釈: | |
反応性: | Human |
免疫原: | Human CHRFAM7A |
憲法: | Liquid |
ストレージバッファ: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles. |
精製方法: | Antigen Affinity purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Non-conjugated |
シノニム: | CHRNA7 (cholinergic receptor, nicotinic, α 7, exons 5-10) and FAM7A (family with sequence similarity 7A, exons A-E) fusion;CHRFAM7A;CHRNA7;CHRNA7-DR1;D-10;MGC120482;MGC120483 ; |
UniProt Protein Function: | CHRFAM7A: Belongs to the ligand-gated ion channel (TC 1.A.9) family |
UniProt Protein Details: | Protein type:Membrane protein, multi-pass Chromosomal Location of Human Ortholog: 15q13.1 Cellular Component: integral to membrane Molecular Function:extracellular ligand-gated ion channel activity |
NCBI Summary: | The nicotinic acetylcholine receptors (nAChRs) are members of a superfamily of ligand-gated ion channels that mediate fast signal transmission at synapses. The family member CHRNA7, which is located on chromosome 15 in a region associated with several neuropsychiatric disorders, is partially duplicated and forms a hybrid with a novel gene from the family with sequence similarity 7 (FAM7A). Alternative splicing has been observed, and two variants exist, for this hybrid gene. The N-terminally truncated products predicted by the largest open reading frames for each variant would lack the majority of the neurotransmitter-gated ion-channel ligand binding domain but retain the transmembrane region that forms the ion channel. Although current evidence supports transcription of this hybrid gene, translation of the nicotinic acetylcholine receptor-like protein-encoding open reading frames has not been confirmed. [provided by RefSeq, Jul 2008] |
UniProt Code: | Q494W8 |
NCBI GenInfo Identifier: | 91208254 |
NCBI Gene ID: | 89832 |
NCBI Accession: | Q494W8.1 |
UniProt Related Accession: | Q494W8 |
Molecular Weight: | 46kDa |
NCBI Full Name: | CHRNA7-FAM7A fusion protein |
NCBI Synonym Full Names: | CHRNA7 (exons 5-10) and FAM7A (exons A-E) fusion |
NCBI Official Symbol: | CHRFAM7A |
NCBI Official Synonym Symbols: | D-10; CHRNA7; NACHRA7; CHRNA7-DR1 |
NCBI Protein Information: | CHRNA7-FAM7A fusion protein |
UniProt Protein Name: | CHRNA7-FAM7A fusion protein |
UniProt Synonym Protein Names: | CHRNA7-DR1; D-10 |
Protein Family: | CHRNA7-FAM7A fusion protein |
UniProt Gene Name: | CHRFAM7A |
UniProt Entry Name: | CRFM7_HUMAN |