CFHR1 Antibody, Biotin conjugated (PACO61609)
- SKU:
- PACO61609
- Product type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Application:
- ELISA
- Antibody type:
- Polyclonal
- Conjugation:
- Biotin
Frequently bought together:
Description
抗体名: | CFHR1 Antibody, Biotin conjugated (PACO61609) |
抗体コード: | PACO61609 |
サイズ: | 50ug |
宿主種: | Rabbit |
申し込み: | ELISA |
推奨される希釈: | |
反応性: | Human |
免疫原: | Recombinant Human Complement factor H-related protein 1 protein (132-221AA) |
憲法: | Liquid |
ストレージバッファ: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
精製方法: | >95%, Protein G purified |
抗体のクローン性: | Polyclonal |
アイソタイプ: | IgG |
Conjugate: | Biotin |
バックグラウンド: | Involved in complement regulation. The dimerized forms have avidity for tissue-bound complement fragments and efficiently compete with the physiological complement inhibitor CFH. Can associate with lipoproteins and may play a role in lipid metabolism. |
シノニム: | Complement factor H-related protein 1, FHR-1, H factor-like protein 1, H-factor-like 1, H36, CFHR1, CFHL, CFHL1, CFHL1P, CFHR1P, FHR1, HFL1, HFL2 |
UniProt Protein Function: | CFHR1: Might be involved in complement regulation. Can associate with lipoproteins and may play a role in lipid metabolism. |
UniProt Protein Details: | Protein type:Secreted, signal peptide; Secreted Chromosomal Location of Human Ortholog: 1q32 Cellular Component: extracellular space Biological Process: complement activation Disease: Macular Degeneration, Age-related, 1; Hemolytic Uremic Syndrome, Atypical, Susceptibility To, 1 |
NCBI Summary: | This gene encodes a secreted protein belonging to the complement factor H protein family. It binds to Pseudomonas aeruginosa elongation factor Tuf together with plasminogen, which is proteolytically activated. It is proposed that Tuf acts as a virulence factor by acquiring host proteins to the pathogen surface, controlling complement, and facilitating tissue invasion. Mutations in this gene are associated with an increased risk of atypical hemolytic-uremic syndrome. [provided by RefSeq, Oct 2009] |
UniProt Code: | Q03591 |
NCBI GenInfo Identifier: | 218512041 |
NCBI Gene ID: | 3078 |
NCBI Accession: | Q03591.2 |
UniProt Related Accession: | Q03591 |
Molecular Weight: | |
NCBI Full Name: | Complement factor H-related protein 1 |
NCBI Synonym Full Names: | complement factor H related 1 |
NCBI Official Symbol: | CFHR1 |
NCBI Official Synonym Symbols: | CFHL; FHR1; HFL1; HFL2; CFHL1; H36-1; H36-2; CFHL1P; CFHR1P |
NCBI Protein Information: | complement factor H-related protein 1 |
UniProt Protein Name: | Complement factor H-related protein 1 |
UniProt Synonym Protein Names: | H factor-like protein 1; H-factor-like 1; H36 |
UniProt Gene Name: | CFHR1 |
UniProt Entry Name: | FHR1_HUMAN |